Results 211 to 220 of about 36,597 (305)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Integrated optomechanical ultrasonic sensors with nano-Pascal-level sensitivity. [PDF]

Light Sci Appl
Cao X, Yang H, Wang M, Hu ZG, Wu ZL, Wang Y, Liu JF, Zhou X, Li J, Lao C, Yang QF, Li BB.   +11 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

3D Geometry-Aware Efficient Feature Matching for Weakly Textured Scenes. [PDF]

J Imaging
Sun L, Yan Y, Yang W, Qin W.
europepmc   +1 more source

Microstrip Configurations of Reflective-Mode Phase-Variation Permittivity Sensors Based on Weakly Coupled Step Impedance Resonators (SIR)

This paper presents and experimentally validates various topologies of one-port reflective-mode phase-variation permittivity sensors based on weakly coupled step impedance resonators (SIRs), the sensing elements, implemented in microstrip technology. The differences between such topologies concern the specific configuration, either series or parallel ...
Borràs-Sarsa, Joaquim||, Casacuberta Orta, Pau||, Vélez Rasero, Paris||, Su, Lijuan||, Canalias, Xavier||, Martín, Ferran||   +5 more
openaire   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Multiple reflection: A Route to enhanced sensitivity in beam-deflection optical ultrasound sensing. [PDF]

Photoacoustics
You Y, Niu P, Ma Y, Zhang P.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Intelligent Soft Opto-Magnetic Robot for Minimally Invasive Interventional Therapy. [PDF]

Adv Sci (Weinh)
Guo J, Guo X, Wei J, Jiang M, Su Q, Xia X, Li Z, Cai R, Ma J, Fu B, Li M, Zhong J, Xu L, Ji X.   +13 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source