Results 131 to 140 of about 453,989 (315)

#FramingFragmentsofThought – Exploring the Role of Social Media, in Developing Emergent Reflective Practitioners in Initial Teacher Training

open access: yesJETEN, 2017
#framingfragmentsofthoughtconsiders the changing dynamic of teacher education and the relevance of digital pedagogical changes in course instruction.
Chris Warnock
doaj  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Online reflective diaries - using technology to strengthen the learning experience [PDF]

open access: yes, 2010
Internet based technologies have benefits for students and staff in terms of time and information sharing. Students at the University of Glasgow were required to engage in reflective writing, with tutor support, as part of their course assessment.
Tierney, A., Butler, E., Tatner, M.
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The use of reflective journals in the promotion of reflection and learning in post registration nursing students [PDF]

open access: yes
Reflective journal writing has frequently been used in nursing and other health care fields as an educational strategy to promote reflection and learning.
Chirema, Kathleen Dympna
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The role of reflective functioning in mediating the relationship between attachment style and psychopathology [PDF]

open access: yes, 2014
This thesis focuses on the association between attachment style and mentalizing ability and the extent to which the two are predictive of psychopathology.
Ghossain, D
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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