Results 241 to 250 of about 885,510 (305)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source
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Reflection, reflective practice and embodied reflective practice

Body, Movement and Dance in Psychotherapy, 2013
Although widely employed in professional practice of all kinds, ‘reflection’ and ‘reflective practice’ can be considered ‘success words’. That is, they elicit positive and supportive responses and yet the concepts are vague, ill-defined, contradictory and reflective skills can be hard to teach. Using examples from education and somatic movement therapy,
Jennifer Leigh, Richard Bailey
openaire   +1 more source

Reflective practice

Nursing Standard, 1994
Aim and intended learning outcomes The aim of this article is to encourage and enable nurses to develop an understanding of the nature of reflective practice and how this may enhance personal and professional learning. After reading this article, the nurse should be able to.
openaire   +2 more sources

Understanding reflective practice

Nursing Standard, 2016
The Nursing and Midwifery Council (NMC) requires that nurses and midwives use feedback as an opportunity for reflection and learning, to improve practice. The NMC revalidation process stipulates that practitioners provide examples of how they have achieved this.
Jacqueline Sian, Nicol, Isabel, Dosser
openaire   +2 more sources

Reflections on Reflective Practice

Canadian Journal of Occupational Therapy, 2001
In recent years, a wide range of professions have adopted ‘reflective practice’ as an approach to professional development, and many professions have made it a mandatory dimension of their membership credentialling process. Despite the fact that it has been widely taken up in the professional world, there are many different conceptualizations and ...
openaire   +2 more sources

Reflective Practice

2017
Learning from professional errors in social work is vital for successful reflective practice. With plenty of practice examples and questions for reflection, this is essential reading for social work students, practitioners and managers.
openaire   +2 more sources

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