Results 171 to 180 of about 1,810,512 (351)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Identifikasi Kedalaman Berpikir Reflektif Calon Guru Matematika dalam Pemecahan Masalah Matematika melalui Taksonomi Berpikir Reflektif Berdasarkan Gaya Kognitif

open access: yesJurnal Elemen, 2020
Reflective thinking in solving mathematical problems allows students to carry out a reinterpretation process in which cognitive activity involves analytical and decision-making activities on what has been done before.
Agustan Syamsuddin
doaj  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Revisiting On-Line Discussion as Practice for Reflective Thinking in Three Sequential Classes

open access: yes, 2008
In a previous study, the authors questioned the potential of an on-line environment for increasing productive reflection in three sequential education classes.
Dittrich, Charles   +3 more
core  

Embedding reflective thinking on approaches to learning - moving from pilot study to developing institutional good practice [PDF]

open access: yes, 2011
Aim Asking undergraduates to reflect on their approaches to learning involves the individuals in effort and activity they may well consider to be an unwanted addition to their normal studies: unless the activity has clear links in their minds with their
Edwards, Chris
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Hannah Arendt and the law and ethics of administration : bureaucratic evil, political thinking and reflective judgment [PDF]

open access: yes, 2012
After the absurd terrorism and violence of the totalitarianism and bureaucratic administrative and legal systems of the 20th century it does not give any meaning to rationalize harm as meaningful evil that even though it is evil may have some importance ...
Rendtorff, Jacob Dahl
core  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Stop, Think, Plan, Reflect

open access: yesWestern Journal of Emergency Medicine, 2023
Ingram, Taylor   +9 more
openaire   +3 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

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