Results 171 to 180 of about 267,336 (313)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Volumetric and En Face Hyper-Reflective Henle Fiber Layer in Age-Related Macular Degeneration. [PDF]

Invest Ophthalmol Vis Sci
Wang CX, Wang J, Hormel TT, Hwang TS, Lujan BJ, Bailey ST, Huang D, Jia Y.   +7 more
europepmc   +1 more source

ROLE OF SCAFFOLDING FOR REFLECTIVE THINKING ON THE MATHEMATICAL PROBLEM SOLVING

, 2022
Irianto Aras, Enditiyas Pratiwi, A. Wilda Indra Nanna, Mardyanto Barumbun   +3 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Soft X-ray imaging with coherence tomography in the water window spectral range using high-harmonic generation. [PDF]

Light Sci Appl
Reinhard J, Wiesner F, Hennecke M, Sidiropoulos T, Kaleta S, Späthe J, Abel JJ, Wünsche M, Schmidl G, Plentz J, Hübner U, Freiberg K, Apell J, Lippmann S, Schnürer M, Eisebitt S, Paulus GG, Fuchs S.   +17 more
europepmc   +1 more source

Using Farrell's Framework for Developing EFL Reflective Writing Skills among Student Teachers in Primary English Section [PDF]

الاء هاشم عبد الفتاح محمد
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Towards lasing systems for distributed fibre sensing. [PDF]

Light Sci Appl
Thévenaz L.
europepmc   +1 more source

Using blogs to help language students to develop reflective learning strategies: Towards a pedagogical framework

, 2010
Tríona Hourigan, Liam Murray
openalex   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source