Results 191 to 200 of about 267,336 (313)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Vertical motions in clouds from EarthCare satellite and a global storm-resolving modeling. [PDF]
Roh W +5 more
europepmc +1 more source
Brahmam Mirror Number: A Reflective Symmetry Principle in Digital Arithmetic
Odugu, Brahmam
openalex +1 more source
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Pressure and Temperature Dependence of Optical Resonance Wavelength (ORW) of Large-Element Surface-Micromachined Optical Ultrasound Transducers (SMOUTs). [PDF]
Upadhyay K, Fang C, Yan Z, Li X, Zou J.
europepmc +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Optical Bound States in the Continuum in Subwavelength Gratings Made of an Epitaxial van der Waals Material. [PDF]
Pruszyńska-Karbownik E +11 more
europepmc +1 more source
Toward a reflective culture of teaching: a landscape for praxis
James P Golubich
openalex +1 more source

