Results 41 to 50 of about 15,581 (263)

A single sequence of intermittent hypoxia does not alter stretch reflex excitability in able‐bodied individuals

open access: yesExperimental Physiology
Spasticity attributable to exaggerated stretch reflex pathways, particularly affecting the ankle plantar flexors, often impairs overground walking in persons with incomplete spinal cord injury.
Andrew Q. Tan   +4 more
doaj   +1 more source

Gait simulation in children with cerebral palsy using a three-dimensional neuromuscular skeleton model

open access: yesNihon Kikai Gakkai ronbunshu, 2021
Cerebral palsy (CP) causes abnormal gait pattern due to increased stretch reflex and contracture in specific muscles. Increased stretch reflexes in CP are caused by increased activation of muscle spindles due to increased sensitivity of gamma motor ...
Ryosuke YUMOTO   +3 more
doaj   +1 more source

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou   +6 more
wiley   +1 more source

Diet‐induced obesity decreases rate‐dependent depression in the Hoffmann’s reflex in adult mice

open access: yesPhysiological Reports, 2019
Obesity is associated with balance and motor control deficits. We have recently shown that Group Ia muscle spindle afferents, the sensory arm of the muscle stretch reflex, are less responsive in mice fed a high‐fat diet.
Gerard L. Nguyen   +5 more
doaj   +1 more source

Translations of the Humeral Head Elicit Reflexes in Rotator Cuff Muscles That Are Larger Than Those in the Primary Shoulder Movers

open access: yesFrontiers in Integrative Neuroscience, 2022
Muscle activation helps stabilize the glenohumeral joint and prevent dislocations, which are more common at the shoulder than at any other human joint. Feedforward control of shoulder muscles is important for protecting the glenohumeral joint from harm ...
Constantine P. Nicolozakes   +11 more
doaj   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

open access: yesArthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart   +5 more
wiley   +1 more source

Increased Ankle Plantar Flexor Stiffness Is Associated With Reduced Mechanical Response to Stretch in Adults With CP

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Hyperexcitable stretch reflexes are often not present despite of other signs of spasticity in people with brain lesion. Here we looked for evidence that increased resistance to length change of the plantar flexor muscle-fascicles may contribute to a ...
Jakob Lorentzen   +6 more
doaj   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo   +9 more
wiley   +1 more source

Spasticity mechanisms - for the clinician

open access: yesFrontiers in Neurology, 2010
Spasticity, a classical clinical manifestation of an upper motor neuron lesion, has been traditionally and physiologically defined as a velocity dependent increase in muscle tone caused by the increased excitability of the muscle stretch reflex ...
Ambar eChakravarty, Angshuman eMukherjee
doaj   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki   +6 more
wiley   +1 more source

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