Results 171 to 180 of about 585,047 (286)

Mechanical Environment Afforded by Engineered Hydrogel Critically Regulates Survival of Neural Stem Cells Transplanted in the Injured Spinal Cord via Piezo1‐Mediated Mechanotransduction

Advanced Science, EarlyView.
Neural stem cell transplantation shows promise for spinal cord repair, but poor graft survival limits therapeutic efficacy. This study demonstrates that increasing hydrogel stiffness from 10% to 16% concentration significantly enhances transplanted neural stem cell survival through Piezo1‐mediated mechanotransduction, revealing mechanical properties as
Hee Hwan Park, Yurim Kim, Byeong Seong Jang, Simay Genişcan, Dong Hoon Hwang, Yeojin Seo, Seung‐Ah Jee, Hyo Gyeong Seo, Hyung Soon Kim, Ariandokht Einisadr, Ho‐Jeong Kim, Seolhee Lee, Sangwoo Kwon, Kyung Sook Kim, Kang In Lee, Jae Young Lee, Joo Min Park, Young‐Min Kim, Soo‐Chang Song, Byung Gon Kim   +19 more
wiley   +1 more source

Prospective evaluation of spinal reflex excitability and perceived ankle instability following acute lateral ankle sprain in collegiate basketball players. [PDF]

BMC Sports Sci Med Rehabil
Terada M, Taniyama D, Isaka T.
europepmc   +1 more source

Midkine‐Mediated Microglia Activation after Renal Injury Promotes Cognitive Impairment Following Ischemic Renal Injury

Advanced Science, EarlyView.
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu, Bixiao Liu, Yu Yang, Tao Meng, Yuanyuan Chang, Yao Peng, Jia Guo, Zhuqing Wang, Hongqian Guo, Liuhua Zhou, Xiaozhi Zhao   +10 more
wiley   +1 more source

The Soleus H-Reflex as a Biomarker of Post-Injury Spasticity in Spinal Cord Injury: A Conceptual Pilot Study. [PDF]

NeuroRehabilitation
Bourgeois H, Genet H, MacMahon M, Richard-Denis A, Mac-Thiong JM, de Beaumont L, Barthelemy D.   +6 more
europepmc   +1 more source

Relationship between primitive reflex values and gross motor abilities in children with spastic cerebral palsy

, 2020
Tammi H Ryani Daeng, Mita Noviana, Fitrah Nasaruddin   +2 more
openalex   +1 more source

Effect of click-repetition rate on acoustic reflex growth [PDF]

, 1993
Vishakha W. Rawool
openalex   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

Advanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan, Mengyao Zhang, Haiyue Guo, Yan Xu, Chenjie Xu, Fan Hu, Yinbing Pan, Xian Wang, Wentao Liu, Chun‐Yi Jiang   +9 more
wiley   +1 more source

Oculocardiac reflex causing bradycardia in a trauma patient following firearm injury. [PDF]

Trauma Case Rep
Geller JE, Daneshpooy S, Block S, Kohli M, Lundy M.   +4 more
europepmc   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Understanding the pathophysiology of reflex epilepsy using simultaneous EEG‐fMRI

, 2014
Manglore Sandhya, Rose Dawn Bharath, Rajanikant Panda, Sawarya Chandra, Naveen Kumar, Lija George, A. Thamodharan, Arun Kumar Gupta, P Satishchandra   +8 more
openalex   +2 more sources