Results 101 to 110 of about 248,421 (302)

Halitosis and tongue coating in patients with erosive gastroesophageal reflux disease versus nonerosive gastroesophageal reflux disease [PDF]

, 2013
OBJECTIVE The aim of this study was to investigate whether patients with diagnosed erosive gastroesophageal reflux disease (ERD) have an increased probability of halitosis and tongue coating compared to patients with nonerosive gastroesophageal reflux
Wilder-Smith, Clive H., Lussi, Adrian, Kislig, Karin, Bornstein, Michael, Wilder-Smith, Clive H, Seemann, Rainer, Bornstein, Michael M.   +6 more
core   +2 more sources

Targeted Degradation of Picornaviral 3C Protease via PROTACs Confers High Barrier to Viral Resistance and Broad‐Spectrum Antiviral Activity

Advanced Science, EarlyView.
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng, Junyu Chen, Yingyue Pang, Yuanyuan Zhang, Siqian Chen, Guoliang You, Xiaoman Tian, Zhongxin Xu, Jing Wang, Luqing Shang   +9 more
wiley   +1 more source

Trajectory study of early postoperative reflux and related symptoms in patients with esophageal cancer

Huli yanjiu, 2023
ObjectiveTo evaluate the symptom trajectory by ecological instantaneous assessment method，and to explore the change　 trajectory and correlation between early postoperative reflux and related symptoms in patients with esophageal cancer.MethodsA total of ...
ZHAO Yuqing, LI Huixia, SUN Xueying, MI Jiaying, LU Qi, ZHAO Yue   +5 more
doaj  

Regulating Droplet Dynamics via Wormlike Micelle Networks: From Splash Suppression to Precise Confined Spreading

Advanced Science, EarlyView.
As displayed in Graphical Abstract image.tif, a molecular‐design strategy precisely tailors high‐speed droplet dynamics through programmed surfactant co‐assembly. The structural transition into an entangled wormlike micelle network completely suppresses stochastic splashing on fibrous substrates.
Shuling Liu, Beibei Xie, Xingyue Lou, Yu Deng, Lei Wang, Jiawei Li, Dongming Qi   +6 more
wiley   +1 more source

Sheet‐Size‐Dependent Mosaicity of 2D Phyllosilicate Membranes

Advanced Science, EarlyView.
This study explores how the size of 2D vermiculite sheets affects the structure of laminar membranes. High‐resolution x‐ray diffraction reveals how sheet size governs structural disorder and crystallinity. These changes directly impact ion permeability.
Min A Kim, Paul A. Fenter, Sang Soo Lee, Katrina I. Sparks, Yining Liu, Jeffrey W. Elam, Seth B. Darling   +6 more
wiley   +1 more source

TIPURI ȘI SISTEME DE CLASIFICARE ALE REFLUXULUI VENOS ÎN BOALA VENOASĂ CRONICĂ: SINTEZĂ NARATIVĂ DE LITERATURĂ

Arta Medica, 2022
Obiective. Boala venoasă cronică, la momentul actual, reprezintă una dintre cele mai frecvente cauze ale spitalizărilor în secțiile de profil chirurgical, datorită incidenței sale înalte și a unui spectru vast de manifestări clinice.
Luminita Vescu, Dumitru Casian
doaj  

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Management of gastroesophageal reflux disease in adults: a pharmacist’s perspective

Integrated Pharmacy Research and Practice, 2018
Brett MacFarlane1,2 1Australian College of Pharmacy, Canberra, ACT, Australia; 2Faculty of Health, Queensland University of Technology, Brisbane, QLD, Australia Abstract: Gastroesophageal reflux disease (GERD) is a common gastrointestinal diagnosis, a ...
MacFarlane B
doaj  

Postnasal Drip and Nasal Endoscopy: Localization and Association With Clinical Features

OTO Open
Objective Postnasal drip (PND) is a common symptom that is difficult to verify with a traditional examination. Nasal endoscopy has the potential to improve the diagnostic process by confirming the presence and location of mucus.
Jenilkumar H. Patel, Nicholas Mankowski, Robbie A. Beyl, Manal S. Malik, Andrew Parker, Edward D. McCoul   +5 more
doaj   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source