Stepwise Synthesis of Tetrabenzotriazaporphyrins (TBTAPs) and Their Open 2‐ and 3‐Ring Fragments
Unexpected reaction pathways to porphyrin‐phthalocyanine hybrids are uncovered by the synthesis of “half‐macrocycle” fragments and subsequent macrocyclization. Rather than the expected 2:2 “ABBA” product, the 3:1 “ABBB” hybrid is isolated as the only macrocyclic product.
Jacob Gretton +10 more
wiley +1 more source
Efficacy and safety of foam sclerotherapy for great saphenous vein reflux: a systematic review and meta-analysis of RCTs. [PDF]
Wang J +6 more
europepmc +1 more source
A Unified Approach for the Synthesis of Conformationally Locked and sp2‐sp3 Fused Hybrids
This study presents a systematic platform to build rigid sp2–sp3 hybrids via benzyne cycloadditions. Arene‑fused bicyclic oxa‐, aza‐, and carbocycles are converted into medicinally relevant amino acids and applied to Enalapril analogues synthesis. The hybrids combine aromatic interactions with 3D rigidity, tuning lipophilicity, pKa, and solubility ...
Ervis Saraci +8 more
wiley +1 more source
A double‐headed bis‐guanine (G) nucleotide (GG) was evaluated as a noncanonical building block in G‐quadruplexes (G4s). Biophysical and computational analyses reveal that GG can directly participate in G‐tetrads and strongly stabilize G4s in a position‐ and topology‐dependent manner. These findings establish design rules for using GG to engineer highly
Krista Urup +5 more
wiley +1 more source
Vietnam Association of Gastroenterology (VNAGE) guideline on the management of gastroesophageal reflux disease. [PDF]
Dao HV +27 more
europepmc +1 more source
Seven novel supramolecular photosensitizers based on benzo[c][1,2,5]thiadiazole (BTZ) tethered to calix[4]arene (C[4]) scaffolds are reported with facile, scalable, and selective syntheses. Their abilities to produce singlet oxygen have been tested through the photo‐oxidation of α‐terpinene.
Leonardo Amicosante +6 more
wiley +1 more source
Beyond Reflux Grade: Long-Term Outcomes of Children with Grade 1 Vesicoureteral Reflux. [PDF]
Deliağa H +3 more
europepmc +1 more source
Laparoscopic Fundoplication Using the Excluded Stomach Versus Conversion to Roux-en-Y Gastric Bypass for Refractory Reflux After One-Anastomosis Gastric Bypass: A Retrospective Comparative Analysis of Safety and 1-Year Outcomes. [PDF]
Soprani A +3 more
europepmc +1 more source
Coexistence of PYCR1-related cutis laxa and bilateral grade V vesicoureteral reflux with reflux nephropathy: A case report. [PDF]
Derakhshan D, Bashir F, Derakhshan A.
europepmc +1 more source

