The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome
Biological Reviews, EarlyView.ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke +2 more
wiley +1 more source
Dual-suture fundoplication for anti-reflux reconstruction after proximal gastrectomy: a single-center retrospective case series. [PDF]
BMC SurgYan YX +8 more
europepmc +1 more source
Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea
Chronic Diseases and Translational Medicine, EarlyView.Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy +3 more
wiley +1 more source
Comment on: Diagnostic accuracy of mean nocturnal basal impedance and other complementary tests for the diagnosis of gastroesophageal reflux disease according to the new Lyon criteria. [PDF]
Ther Adv GastroenterolBertin L, Savarino EV.
europepmc +1 more source
Research Progress of Polyoxometalate‐Integrated Frameworks: Syntheses, Properties, and Applications
ChemistryEurope, EarlyView.This review systematically summarizes the integration of polyoxometalates with covalent organic frameworks, metal‐organic frameworks, hydrogen‐bonded organic frameworks, and emerging porous hosts. It highlights synergistic effects, synthesis strategies, and applications in catalysis, energy storage, sensing, and biomedicine, while addressing current ...
De‐Yin Wang +6 more
wiley +1 more source
Preoperative Hill's classification as a predictor of postoperative gastroesophageal reflux disease following laparoscopic sleeve gastrectomy: a prospective multicenter study from Egypt. [PDF]
BMC SurgSemeya AA +5 more
europepmc +1 more source
ChemistryEurope, EarlyView.Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn +6 more
wiley +1 more source