Results 61 to 70 of about 182,257 (211)

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

The assessment of patients with non-erosive gastroesophageal reflux disease by using the Bravo® pH monitoring system

open access: yesSanamed, 2022
Background and aim: Gastroesophageal reflux disease (GERD) is a common disease in the world. GERD is always treated with drugs. The Bravo® wireless pH monitoring system is a good technique. The Bravo® may affect increasing the specificity and sensitivity
Gök Mehmet, Gencdal Genco
doaj  

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

open access: yesAdvanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao   +10 more
wiley   +1 more source

The effect of extraction method on the major constituents and biological effects of Trachyspermum ammi L. fruits [PDF]

open access: yesResearch Journal of Pharmacognosy, 2018
Background and objectives: Variety of extraction methods coupled with definite solvents could increase the removal rate ofmajor constituents from plants.
F. Farjadmand   +8 more
doaj  

Development of automated intravenous blood infusion monitoring system using load cell sensor

open access: yesJournal of Applied Sciences and Environmental Management, 2018
This paper presents an automated intravenous blood infusion unit to prevent a reflux using a load cell sensor. Intravenous infusion is frequently used in the hospital for patients’ management and treatments such as dehydration and surgical operations ...
O.O.E. Ajibola   +2 more
doaj   +1 more source

A Novel Approach Based on Acceptor–Donor–Acceptor Type Molecules Enhances the Therapeutic Efficacy and Safety of Photothermal Therapy for Osteosarcoma

open access: yesAdvanced Science, EarlyView.
Jin et al. developed IEICO‐F nanoparticles with enhanced photothermal conversion efficiency via optimized push‐pull effect. Under 808 nm laser, these nanoparticles effectively generated heat to kill osteosarcoma cells and exhibited significant tumor suppression in vivo. Therefore, this novel A‐D‐A type molecule‐based photothermal therapy strategy holds
Zhijian Jin   +9 more
wiley   +1 more source

GLS1 Orchestrates Exosome‐Mediated Tumor‐Endothelial Communication to Facilitate Angiogenesis

open access: yesAdvanced Science, EarlyView.
This study reveals a previously unappreciated, non‐metabolic function of GLS1 in the control of tumor angiogenesis via exosome‐mediated CAV1‐TNC signaling, indicating that therapeutic targeting of GLS1 may offer a dual benefit by simultaneously suppressing tumor metabolic activity and angiogenic processes in head and neck cancer. ABSTRACT Glutaminase 1
Jianqiang Yang   +9 more
wiley   +1 more source

Management of gastroesophageal reflux disease in adults: a pharmacist’s perspective

open access: yesIntegrated Pharmacy Research and Practice, 2018
Brett MacFarlane1,2 1Australian College of Pharmacy, Canberra, ACT, Australia; 2Faculty of Health, Queensland University of Technology, Brisbane, QLD, Australia Abstract: Gastroesophageal reflux disease (GERD) is a common gastrointestinal diagnosis, a ...
MacFarlane B
doaj  

Trajectory study of early postoperative reflux and related symptoms in patients with esophageal cancer

open access: yesHuli yanjiu, 2023
ObjectiveTo evaluate the symptom trajectory by ecological instantaneous assessment method,and to explore the change  trajectory and correlation between early postoperative reflux and related symptoms in patients with esophageal cancer.MethodsA total of ...
ZHAO Yuqing   +5 more
doaj  

Radial, renal and craniofacial anomalies: Baller-Gerold syndrome

open access: yesIndian Journal of Plastic Surgery, 2008
The Baller-Gerold syndrome is a rare syndrome with very few cases published in literature. Craniosynostosis and radial aplasia are striking features, easy to diagnose. However, there are many differential diagnoses.
Jyotsna Murthy   +2 more
doaj   +1 more source

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