Results 41 to 50 of about 16,546 (194)

Detection of Gastroesophageal Reflux Esophagitis Using 2-fluoro-2-deoxy-d-glucose Positron Emission Tomography

The Scientific World Journal, 2012
Background. Gastroesophageal reflux disease (GERD) is a common disease and a major upper gastrointestinal problem. The purpose of the present study is to evaluate the use of noninvasive 2-fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET) to
Min-Kuei Tsai, Hueisch-Jy Ding, Hsueh-Chou Lai, Kuo-Yang Yen, Chia-Ing Li, Yu-Yi Lin, Kai-Yuan Cheng, Keh-Bin Wang, Chia-Hung Kao   +8 more
doaj   +1 more source

Molecular Characterization of Non‐Specific Esophagitis Reveals a Distinct Non‐Eosinophilic Phenotype With Fibrotic Traits

Allergy, EarlyView.
This study comprehensively characterizes non‐specific esophagitis and elucidates eosinophil‐independent fibrosis mechanisms. NSE appears to be a distinct fibrotic phenotype of the esophagus, without any considerable overlap with GERD and other chronic inflammatory disorders such as EoE or lymphocytic esophagitis.
Marc Pfefferle, Darko Stojkov, Dagmar Simon, Emilie Gueguen, Marcin Wawrzyniak, Margaret H. Collins, Mirna Chehade, Evan S. Dellon, Glenn T. Furuta, Ikuo Hirano, Nirmala Gonsalves, Fouad J. Moawad, Luc Biedermann, Alain M. Schoepfer, Alex Straumann, Hans‐Uwe Simon, Thomas Greuter   +16 more
wiley   +1 more source

The Evolution in Understanding the Physiological Causes of Dyspnoea in Large Hiatal Herniation: A Narrative Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background The symptomatology of large hiatus hernia (LHH) has been historically poorly understood, with cardiorespiratory symptoms caused by LHH being underappreciated by clinicians. This study reports on the mechanisms of dyspnoea in LHH through a historical review of symptoms and evolved physiological literature, discussing likely causation.
Arunan Mahendravarman, Fienne Cordeschi, Gregory Leighton Falk   +2 more
wiley   +1 more source

Impact of Upper Gastrointestinal Involvement on Clinical Outcomes in Paediatric Inflammatory Bowel Disease

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to assess the clinical implications of upper gastrointestinal (UGI) involvement in paediatric inflammatory bowel disease (IBD). Methods This retrospective cohort study included children diagnosed with IBD between 2010 and 2023, who underwent a UGI endoscopic evaluation at diagnosis and were followed for at least ...
Ofek Aloni, Adi Anafy, Hadar Moran‐Lev, Achiya Amir, Alma Ziv, Reut Doyev, Tut Galai, Shlomi Cohen, Anat Yerushalmy‐Feler   +8 more
wiley   +1 more source

Eosinophilic Oesophagitis Beyond the Oesophagus: High Prevalence of Chronic Rhinosinusitis‐Type Symptoms and Their Impact on Symptom Severity in Swiss EoE Cohort Study Patients

Alimentary Pharmacology &Therapeutics, EarlyView.
Among 211 prospectively followed Swiss patients with eosinophilic oesophagitis, chronic rhinosinusitis was two‐ to three‐fold more common than in the general population. It was associated with greater oesophageal symptom severity and, in a quarter of cases, was experienced by patients as more debilitating than the underlying oesophageal disease ...
Gebhardt Aidan, Kreienbühl Andrea, Greuter Thomas, Schlag Christoph, Nennstiel Simon, Saner Catherine, Rossel Jean‐Benoit, Mauthe Tina, M. Meerwein Christian, Schoepfer Alain, B. Soyka Michael, Straumann Alex, Biedermann Luc, on behalf of the Swiss EoE Cohort Study Group, Patrick Aepli, Luc Biedermann, Ruggero Biral, Carine Blanchard, Simon Buetikofer, Emanuel Burri, Joachim Diebold, Carolien Dietrich, Annett Franke, Michèle Gwerder, Thomas Greuter, Chantal Hasler, Wolfram Jochum, Tanay Kaymak, Andrea Kreienbühl, Katline Metzger‐Peter, Fritz Murray, Simon Nennstiel, Peter Netzer, Jan Hendrik Niess, Gabrielle Reichhart, Cristiana Quattropani, Elodie Ristorcelli, Jean‐Benoit Rossel, Ekaterina Safroneeva, Catherine Saner, Alain Schoepfer, Philip Schreiner, Christine Sempoux, Dagmar Simon, Hans‐Uwe Simon, Alex Straumann, Sven Trelle, Achim Weber, Niels Willi, Elina Wuethrich, Marcel Zwahlen, Michael Scharl, Marcin Wawrzyniak   +52 more
wiley   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

The Prevalence of Reflux Esophagitis in the Elderly and Its Associated Risk Factors

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2016
Background: Reflux esophagitis is a common problem in the elderly. Compare to the Western Countries, esophageal cancer where reflux esophagitis is the most predominant risk factor is considered rare in Asia.
Cosmas Rinaldi A Lesmana, Billy Angga, Levina S Pakasi, Waldemar Simanjuntak, Laurentius A Lesmana   +4 more
doaj  

Esophageal Anisakiasis Accompanied by Reflux Esophagitis.

Internal Medicine, 1997
A case with esophageal anisakiasis accompanied by reflux esophagitis is described. A 38-year-old man visited our hospital with complaints of heartburn and disturbance of food passage about seven hours after eating raw cuttlefish. The first esophagogastroscopy revealed an anisakis larva invading the squamocolumnar junction.
URITA, Yoshihisa, NISHINO, Mamoru, KOYAMA, Hiroshi, KONDO, Eisaku, NARUKI, Yukihiko, OTSUKA, Sachio   +5 more
openaire   +3 more sources

From Reflux Esophagitis to Esophageal Adenocarcinoma [PDF]

Digestive Diseases, 2016
Reflux esophagitis causes Barrett's metaplasia, an abnormal esophageal mucosa predisposed to adenocarcinoma. Medical therapy for reflux esophagitis focuses on decreasing gastric acid production with proton pump inhibitors. We have reported that reflux esophagitis in a rat model develops from a cytokine-mediated inflammatory injury, not from a caustic ...
openaire   +2 more sources

Mechanisms underpinning the progression of nondysplastic Barrett's oesophagus to cancer

The FEBS Journal, EarlyView.
Barrett's oesophagus confers a low but significant cancer risk. The condition is common but we do not have effective biomarkers to identify susceptible patients. We believe that there is no single factor that determines cancer risk and an understanding of the combinations of interactions (via gene expression and natural selection) between the Barrett's
Yannick H. Derwa, Meng‐Lay Lin, Stuart A. C. McDonald   +2 more
wiley   +1 more source