Results 151 to 160 of about 2,878,418 (399)

A Full‐Range Proximity‐Tactile Sensor Based on Multimodal Perception Fusion for Minimally Invasive Surgical Robots

open access: yesAdvanced Science, EarlyView.
A full‐range proximity‐tactile sensing module is developed for safe operation of surgical robots, which performs multimodal fusion perception through ultrasonic sensor for long‐range proximity detection, capacitive sensor for close‐range proximity sensing, and triboelectric sensor for tactile sensing.
Dongsheng Li   +8 more
wiley   +1 more source

Glucose‐Responsive PAGR1‐Regulated Skeletal Muscle Gene Program Controls Systemic Glucose Homeostasis and Hepatic Metabolism

open access: yesAdvanced Science, EarlyView.
The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding   +19 more
wiley   +1 more source

Paired-eye comparison of endothelial cell density and vault height after implantable collamer lens implantation

open access: yesScientific Reports
In clinical practice, the effect of a high vault on corneal endothelial cells after implantable collamer lens (ICL) implantation remains unclear. Many clinicians theoretically assume that a high postoperative vault leads to rapid endothelial damage, but ...
Hannuy Choi   +4 more
doaj   +1 more source

Perovskite‐Graphene Heterostructure Biosensor Integrated with Biotunable Nanoplasmonic Ternary Logic Gate for Ultrasensitive Cytokine Detection

open access: yesAdvanced Science, EarlyView.
This work proposes the first perovskite/graphene heterostructure‐based FET biosensor with uniquely biotunable ternary logic gating functionality for the detection of human IL6 cytokines. The biosensor integrates a lateral perovskite‐on‐graphene heterostructure phototransistor with a vertical bio‐nano‐photonic filter, achieving ultrahigh sensitivity ...
Jiaxing Sun   +7 more
wiley   +1 more source

Hexokinase‐2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang   +9 more
wiley   +1 more source

Rotational Stability After Implantation of an Aspheric Toric Monofocal IOL with a Double C-Loop Haptic Design in Normal and High Axial Lengths

open access: yesClinical Ophthalmology
Robert Edward T Ang,1 Pedro Tañá-Rivero,2 Francisco Pastor-Pascual,3 Pavel Stodulka,4,5 Martin Slovak,4 Manfred Tetz,6 Isaak Fischinger,7 Jorge Cazal,8 María Gessa,9 Marta Ibarz-Barberá,10 Detlef Holland,11 Thomas Groneberg12 1Asian Eye Institute, Makati
Ang RET   +11 more
doaj  

Capturing the Electrical Activity of all Cortical Neurons: Are Solutions Within Reach?

open access: yesAdvanced Science, EarlyView.
Despite advancements in implantable electrode technology, challenges persist in scaling up these devices to record most of the neuronal activity across the cortex. This review explores the limitations of both rigid and flexible probes, including tissue damage and foreign body response, while also discussing emerging biohybrid strategies.
Attila Kaszás   +5 more
wiley   +1 more source

Magnetically Controllable and Degradable Milliscale Swimmers as Intraocular Drug Implants

open access: yesAdvanced Science, EarlyView.
Magnetically controllable degradable milliscale swimmers (MDMS) offer a promising alternative to commercial intraocular drug implants, reducing complications like implant dislocation and uncontrolled drug release. MDMS achieve high velocities in ocular environments, enable real‐time imaging, and deliver drugs effectively without disrupting retinal ...
Erdost Yildiz   +8 more
wiley   +1 more source

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