Results 201 to 210 of about 710,395 (248)

LigHTS: Biomimetic Hydrogel Photo‐Fabrication for Imaging‐Based Ultra‐High‐Throughput Screening

Advanced Science, EarlyView.
LigHTS removes a key bottleneck for ultra‐high‐throughput screening (UHTS) by enabling biomimetic hydrogel microenvironments to be manufactured directly in standard multiwell plates. A single, collimated UV exposure with formulation‐tuned light penetration patterns an entire plate with UHTS‐grade uniformity (<20% CV), producing structured GelMA films ...
Alessandro Enrico, Sara Rigolli, Julius Zimmermann, Melissa Pezzotti, Eloisa Torchia, Moises Di Sante, Ferdinando Auricchio, Francesco S. Pasqualini   +7 more
wiley   +1 more source

Mechanistic basis of aldose reductase inhibition by phenolics from <i>Achillea fragrantissima</i>: experimental insights and computational validation. [PDF]

3 Biotech
Kamel EM, Abdelrheem DA, Allam AA, Bin-Jumah M, Alkhedhairi S, Alkhayl FFA, Lamsabhi AM.   +6 more
europepmc   +1 more source

Optical Access to Dark Excitons Via Spin–Phonon Fano Interference

Advanced Science, EarlyView.
Dark excitons in quantum dots neither absorb nor emit light and stay hidden from optical spectroscopy. Quantum interference now reveals them: light scattered by acoustic phonons interferes with a phonon‐assisted spin flip between bright and dark exciton, carving a Fano dip into the spectrum whose position gives the bright–dark splitting. Magnetic field,
Janina J. Schindler, Katja Barthelmi, Mikhail M. Glazov, Carlo Sgroi, Sven Scholz, Arne Ludwig, Andreas D. Wieck, Jörg Debus   +7 more
wiley   +1 more source

Synthesis and pharmacokinetic profiling of a novel pyrimidine imidazole based thiosemicarbazone derivative for BRAF inhibition in lung cancer therapy. [PDF]

Discov Oncol
Ekincioğlu Y, Kızıl HE, Güllü E, Özkan EH, Nartop D.   +4 more
europepmc   +1 more source

Loss‐Engineered Terahertz Pixelated Metasensors for Enhanced Molecular Vibrational Fingerprint Sensing

Advanced Science, EarlyView.
This work presents a THz pixelated metasensor that employs loss optimization and spectral overlap for enhanced molecular vibrational fingerprint sensing. The flexible loss rate tuning through the out‐of‐plane dimension allows the device to operate in the optimal fingerprint enhancement condition.
Chenglin Yang, Yuqing Cui, Donghai Han, Yushan Hou, Zhonglei Shen, Andreas Tittl, Liuyang Zhang, Ruqiang Yan, Xuefeng Chen   +8 more
wiley   +1 more source

A Pitstop-2 analog impairs viability of aggressive lung cancer cells by disrupting nuclear pore integrity. [PDF]

Nanoscale Adv
Stefanello ST, Mizdal CR, Konken CP, Haufe G, Shahin V.   +4 more
europepmc   +1 more source

Prepolymerization Enables On‐Demand Viscosity Tuning for Xolography of Soft Hydrogels

Advanced Science, EarlyView.
A facile in situ prepolymerization strategy enables on‐demand viscosity tuning across three orders of magnitude without external thickeners, transforming low‐viscosity resins into printable formulations for Xolography. The approach suppresses sedimentation, lowers curing dose, enables high‐fidelity support‐free fabrication, and produces advanced ...
Xichuan Li, Marcus Reuter, Linguangze Zhuo, Xueheng Dai, Camille Tribout, Nathaniel Corrigan, Jin Zhang, Cyrille Boyer   +7 more
wiley   +1 more source

ACLPred: an explainable machine learning and tree-based ensemble model for anticancer ligand prediction. [PDF]

Sci Rep
Yadav AK, Kim JM.
europepmc   +1 more source

Black Silicon for Solar Fuels

Advanced Science, EarlyView.
Black silicon couples broadband light harvesting with high‐surface‐area catalytic interfaces, offering a versatile photoelectrode platform for solar‐fuel production. Reaction‐specific analysis highlights trade‐offs involving recombination, chemical instability, catalyst‐induced optical shielding, competing reactions, and mass transport.
Neul Ha, Kaiying Wang, Wooseok Yang
wiley   +1 more source

Cheminformatic Identification of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) Inhibitors: A Comparative Study of SMILES-Based Supervised Machine Learning Models. [PDF]

J Pers Med
Lai CH, Kwok APK, Wong KC.
europepmc   +1 more source