Results 141 to 150 of about 395,287 (296)

Synthesis and characterization of ceramic refractories based on industrial wastes. [PDF]

Sci Rep
Khater GA, Romero M, López-Delgado A, Padilla I, El-Kheshen AA, Farag MM, Elmaghraby MS, Nasralla NHS.   +7 more
europepmc   +1 more source

Targeting the PGRN‐BMP Lysosomal Axis With NPs@PGRN Reverses Immunometabolic Dysfunction in Chronic Septic Arthritis

Advanced Science, EarlyView.
Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li, Jiaqi Fan, Tao Sun, Wushi Cui, Jiaxuan Zou, Weinan Yang, Liang Chen, Jian Xiao, Shicheng Wang, Tao Zhang, Jianqiao Hong, An Liu, Haobo Wu   +12 more
wiley   +1 more source

Geological and physicochemical characterization of Kobe Sorsa graphite deposit, Ethiopia. [PDF]

Sci Rep
Emmiru BT, Tsegaye SG, Sahoo PR.
europepmc   +1 more source

Mechanism of carbon nanotube growth in expanded graphite via catalytic pyrolysis reaction using carbores P as a carbon source. [PDF]

Front Chem, 2023
Wang Y, Zhang W, Chen Y, Zeng X, Huang J, Wei H, Tu J.   +6 more
europepmc   +1 more source

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

Advanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim, Ha Kyeong Lee, Zulfikar Azam, Jeong Uk Choi, Riajul Wahab, Na Kyeong Lee, Yoon Gun Ko, So‐Young Choi, Se‐Ra Lee, Wan Seob Shim, Taeeung Kim, In‐San Kim, Farzana Alam, Sang Yoon Kim, Seong Who Kim, Youngro Byun, Taslim A Al‐Hilal   +16 more
wiley   +1 more source

Temperature-invariant crystal-glass heat conduction: From meteorites to refractories. [PDF]

Proc Natl Acad Sci U S A
Simoncelli M, Fournier D, Marangolo M, Balan E, Béneut K, Baptiste B, Doisneau B, Marzari N, Mauri F.   +8 more
europepmc   +1 more source

The Influence of Alumina Bubbles on the Properties of Lightweight Corundum-Spinel Refractory. [PDF]

Materials (Basel), 2023
Xin Y, Jian Y, Yin H, Tang Y, Yuan H, Liu Y.   +5 more
europepmc   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Hydrothermal Fabrication of Low-Dimensional CuO Nanosheets for Enhancing Carbon Reduction Product Selectivity. [PDF]

ACS Omega
Chu W, Guo Q, Zou H, Liu Z, Ren X, Wang X, Chen R, Zhang H, Ni H.   +8 more
europepmc   +1 more source

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

Advanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu, Chen Su, Jianling Liu, Mingyan Xing, Xiaoxia Wu, Lingxia Wang, Xiaoming Zhao, Hanwen Zhang, YangYang Xie, YangYang Wang, Hong Li, Yu Li, Ming Li, Haibing Zhang   +13 more
wiley   +1 more source