Depression in patients with refractory temporal lobe epilepsy [PDF]
OBJECTIVE: To evaluate the comorbidity of depressive disorders in patients with refractory temporal lobe epilepsy (TLE). METHOD: We evaluated 25 consecutive patients with refractory TLE (16 women and 9 men), using semi-structured psychiatric interviews ...
Eleonora Borges Gonçalves +1 more
doaj +2 more sources
Tavistock Adult Depression Study (TADS): a randomised controlled trial of psychoanalytic psychotherapy for treatment-resistant/treatment-refractory forms of depression [PDF]
Background Long-term forms of depression represent a significant mental health problem for which there is a lack of effective evidence-based treatment.
Taylor David +5 more
doaj +3 more sources
An increase in N-Ras expression is associated with development of hormone refractory prostate cancer in a subset of patients [PDF]
Protein expression of H, K and N-Ras was assessed in hormone sensitive and hormone refractory prostate tumour pairs from 61 patients by immunohistochemistry. Expression of H-Ras and K- Ras was not associated with any known clinical parameters.
Traynor, P. +5 more
core +8 more sources
Addictive potential of novel treatments for refractory depression and anxiety. [PDF]
Dusan Kolar Mood Disorders Research and Treatment Service, Department of Psychiatry, Queen’s University, Kingston, Ontario, Canada Abstract: Treatment-resistant mood disorders and anxiety disorders require intensive treatment, but treatment ...
Kolar D.
europepmc +2 more sources
Ketamine Use in Refractory Depression [PDF]
Despite pharmacological advancements, depression continues to be considered the third leading cause of disability in the world. Although depressive symptoms may decrease within a few weeks after beginning typical antidepressants, there are still about ...
Kemmet, McKenzie K.
core +1 more source
Lamotrigine in the treatment of schizoaffective disorder [PDF]
There is accumulating evidence for the efficacy of lamotrigine in the treatment of bipolar disorder, including bipolar depression, both as monotherapy and in combination with sodium valproate.
Grunze, Heinz +2 more
core +1 more source
The lifetime prevalence of depression is reported to be >10%, and it is an important illness that causes various disabilities over a long period of life.
Hiroshi Tateishi +2 more
doaj +1 more source
Nitric oxide formation during cortical spreading depression is critical for rapid subsequent recovery of ionic homeostasis [PDF]
NoCortical spreading depression (CSD) is a temporary disruption of local ionic homeostasis that propagates slowly across the cerebral cortex. Cortical spreading depression promotes lesion progression in experimental stroke, and may contribute to the ...
Urenjak, Jutta A. +5 more
core +1 more source
Surgical treatment for psychiatric disorders, such as obsessive-compulsive disorder (OCD) and depression, using ablative techniques, such as cingulotomy and capsulotomy, have historically been controversial for a number of scientific, social, and ethical
Kyung Won Chang +2 more
doaj +1 more source
Pharmacological treatment of depression in older people [PDF]
In the light of recent National Institute for Clinical Excellence (NICE) and Committee for the Safety of Medicines (CSM) guidance we discuss the importance of the diagnosis of depression in old age and review pharmacological interventions.
Wattis, John +2 more
core +2 more sources

