Results 61 to 70 of about 991 (250)

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He   +10 more
wiley   +1 more source

3D‐Printed Gastrointestinal Stents: In Vivo Evaluation in a Swine Small Bowel Perforation Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Gastrointestinal fistulae and perforations can lead to severe complications including sepsis and patient death. In this work, the efficacy of 3D‐printed gastrointestinal stents composed of poly‐lactic‐acid (PLA) was evaluated in an in vivo swine model.
Gweniviere Capron   +9 more
wiley   +1 more source

Microstructure and Room Temperature Mechanical Properties of Different 3 and 4 Element Medium Entropy Alloys from HfNbTaTiZr System

open access: yesEntropy, 2019
Refractory high entropy alloys (HEA) are promising materials for high temperature applications. This work presents investigations of the room temperature tensile mechanical properties of selected 3 and 4 elements medium entropy alloys (MEA) derived from ...
Jiří Zýka   +6 more
doaj   +1 more source

Modeling of high entropy alloys of refractory elements

open access: yesPhysica B: Condensed Matter, 2012
Abstract Reverting the traditional process of developing new alloys based on one or two single elements with minority additions, the study of high entropy alloys (HEA) (equimolar combinations of many elements) has become a relevant and interesting new field of research due to their tendency to form solid solutions with particular properties in the ...
del Grosso, Mariela Fernanda   +2 more
openaire   +2 more sources

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

Research on Performance Prediction Method of Refractory High-Entropy Alloy Based on Ensemble Learning

open access: yesMetals
Due to the huge component space of refractory high-entropy alloy, the traditional, experimental “trial and error method” can not meet the design requirements.
Guangxiang Tian   +5 more
doaj   +1 more source

Oxygen Evolution Reaction Catalysts for Acidic‐Media CO2 Electrolyzers

open access: yesAdvanced Materials, EarlyView.
Acidic‐media CO2 electroreduction (CO2R) could decarbonize chemical production, despite relying on rare‐earth elements for anodic oxygen evolution reaction (OER). Transferring the learnings from mature sister technologies (water electrolysis) could accelerate technological development.
Mingcheng Huang, Adnan Ozden
wiley   +1 more source

From Copper Nanoparticles to Alumina Encapsulated Porous Layers With Enhanced Mechanical Stability

open access: yesAdvanced Materials Interfaces, EarlyView.
This study analyzes the synthesis‐structure relation of individual Cu nanoparticles and highly porous nanoparticle‐based Cu films using different sputtering‐based nanoparticle sources. The inherent mechanical instability of the films is tackled with Al2O3 encapsulation through atomic layer deposition, enabling 4‐fold increase in critical force in ...
Dominik Gutnik   +6 more
wiley   +1 more source

Additively manufactured high-entropy alloys for hydrogen storage: Predictions

open access: yesHeliyon
This review paper covers an analysis of the empirical calculations, additive manufacturing (AM) and hydrogen storage of refractory high-entropy alloys undertaken to determine the structural compositions, particularly focusing on their applicability in ...
Morena S. Xaba
doaj   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang   +10 more
wiley   +1 more source

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