Results 201 to 210 of about 59,639 (336)

What matters most to people living with epilepsy? A rapid review of qualitative research relating to health outcomes

Epilepsia, EarlyView.
Abstract At present, the outcomes measured and reported in clinical trials for adults with epilepsy are heterogenous and have often not been selected in consultation with people living with epilepsy. As part of a wider project developing a core outcome set for clinical trials for adults with epilepsy (the EPSET Project), a rapid review of the published
James W. Mitchell, John Doherty, Rachel Batchelor, Adam Noble, Anthony Marson   +4 more
wiley   +1 more source

Refractory convulsive status epilepticus in childhood

, 2004
Nikola Dimitrijević, Dragana Bogićević, Dimitrije Nikolić, V Mitic, Nevenka Vunjak, Snežana Rsovac   +5 more
openalex   +2 more sources

Drug discovery and preclinical testing of drug candidates for developmental and epileptic encephalopathies

Epilepsia, EarlyView.
Abstract Drug development for developmental and epileptic encephalopathies (DEEs) follows different strategies on one hand including disease‐targeting precision medicine approaches considering the genetic variants and pathomechanisms in DEEs and on the other hand including therapeutic approaches with novel targets or second‐generation drug candidates ...
Heidrun Potschka, Daniel Pérez‐Pérez
wiley   +1 more source

PAC‐FOS: A novel translational concordance framework identifies preclinical seizure models with highest predictive validity for clinical focal onset seizures

Epilepsia, EarlyView.
Abstract Objective Central to the development of novel antiseizure medications (ASMs) is testing of antiseizure activity in preclinical models. Although various well‐established models exist, their predictive validity across the spectrum of clinical epilepsies has been less clear.
Lyndsey L. Anderson, Kristopher M. Kahlig, Melissa L. Barker‐Haliski, Lillian G. Matthews, Hamish D. Toop, Brian Hannigan, Jacqueline French, H. Steve White, Marcio Souza, Steven Petrou   +9 more
wiley   +1 more source

High-dose midazolam infusion for refractory status epilepticus [PDF]

, 2013
Andres Fernandez, Hector Lantigua, Christine Lesch, Belinda Shao, Brandon Foreman, J. Michael Schmidt, Lawrence J. Hirsch, Stephan A. Mayer, Jan Claassen   +8 more
openalex   +1 more source

Penile urethral anastomosis to the vesico‐urethral junction, after transabdominal wall passage of the penis, as treatment for intrapelvic stent‐related urethral obstruction in a dog

Veterinary Surgery, EarlyView.
Abstract Objective The objective of the present study was to report the outcome of a novel technique of urethral intra‐abdominal anastomosis after transabdominal wall passage of the penis in a dog with stent‐related urethral obstruction. Study design Case report. Animal A seven‐year‐old neutered male Cocker Spaniel.
Armando Foglia, Veronica Cola, Sara Del Magno, Francesco Dondi, Roberta Troia, Stefano Zanardi, Filippo Cinti, Luciano Pisoni   +7 more
wiley   +1 more source

Propofol Infusion Syndrome in Refractory Status Epilepticus [PDF]

, 2013
Woo Sub Hwang, Hye Min Gwak, Dae‐Won Seo   +2 more
openalex   +1 more source

Case Report: Unusual Neurological Features of Leigh Syndrome due to m.8993T>G Pathogenic Variant in the MT‐ATP6 Gene

American Journal of Medical Genetics Part A, Volume 197, Issue 9, September 2025.
ABSTRACT The MT‐ATP6 gene m.8993T>G pathogenic variant has been associated with Leigh syndrome, especially in patients exhibiting a high degree of heteroplasmy. Although patients may present with a wide phenotypic spectrum, characteristic findings include bilateral, symmetric hyperintensities in the basal ganglia and brainstem on brain MRI ...
Ramya Treitel, Julie McLaughlin, Marta Frigeni   +2 more
wiley   +1 more source

Novel anesthetics and other treatment strategies for refractory status epilepticus

, 2009
Andrea O. Rossetti
openalex   +1 more source

Effectiveness of Pyridoxal‐5′‐Phosphate in PNPO Deficiency: A Systematic Review

Journal of Inherited Metabolic Disease, Volume 48, Issue 5, September 2025.
ABSTRACT Pyridox(am)ine 5′‐phosphate oxidase (PNPO) deficiency is an ultrarare inherited neurometabolic disease, characterized by primarily neonatal‐onset B6‐responsive epileptic encephalopathies. Treatment often requires sustainable access to high‐quality pyridoxal‐5′‐phosphate (PLP, i.e., active vitamin B6), although some patients (also) respond to ...
Nina N. Stolwijk, Laura van Dussen, Niels D. Reijnhout, Marion M. M. G. Brands, Bregje Jaeger, Peter T. Clayton, Carla E. M. Hollak, Annet M. Bosch   +7 more
wiley   +1 more source