Results 51 to 60 of about 22,085 (271)

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Epilepsy beyond seizures: a review of the impact of epilepsy and its comorbidities on health-related quality of life in dogs [PDF]

Epilepsy is one of the most common chronic neurological conditions in the dog, estimated to affect 0.6 to 0.75 per cent of dogs. Owners of dogs with epilepsy have previously indicated that their dog's quality of life (QoL) is of greatest importance to ...
Packer, R M A, Volk, H A
core   +1 more source

Commentary on ‘Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children’, with a response from the review authors [PDF]

, 2009
Commentary by David McGillivray, Peter Dayan and Martin Pusic The treatment of an acute convulsion can be a lifesaving intervention, especially in cases where the convulsion is likely to be prolonged or leaves the patient susceptible to aspiration or ...
Dayan, Peter, McGillivray, David, Pusic, Martin   +2 more
core   +2 more sources

Timing of Peri‐Ictal MRI Abnormalities in Status Epilepticus – One Size Does Not Fit All

Annals of Neurology, EarlyView.
Objective We aimed to investigate timing of occurrence of peri‐ictal MRI abnormalities – a potential risk biomarker of status epilepticus‐related cerebral injury (t2). Methods This prospective study enrolled adult patients with status epilepticus and acute magnetic resonance imaging (MRI); patients with peri‐ictal MRI abnormalities underwent follow‐up ...
Pilar Bosque Varela, Lukas Machegger, Tanja Prüwasser, Wanda Lauth, Jürgen Steinbacher, Andreas Oellerer, Georg Zimmermann, Johannes Pfaff, Mark McCoy, Bernardo Crespo Pimentel, Markus Leitinger, Eugen Trinka, Giorgi Kuchukhidze   +12 more
wiley   +1 more source

Evaluation of a clinical tool for early etiology identification in status epilepticus. [PDF]

, 2014
OBJECTIVES: Because early etiologic identification is critical to select appropriate specific status epilepticus (SE) management, we aim to validate a clinical tool we developed that uses history and readily available investigations to guide prompt ...
Alvarez, V., Curley, D., Drislane, F.W., Dworetzky, B.A., Lee, J.W., Rossetti, A.O., Westover, M.B.   +6 more
core   +1 more source

Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice

Annals of Neurology, EarlyView.
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi, John Williamson, Huayu Sun, Suchitra Joshi, Rachel Jane Spera, Savaira Zaib, Supriya Sharma, Chengsan Sun, Andrey Brodovskiy, Ifrah Zawar, Jaideep Kapur   +10 more
wiley   +1 more source

Refractory Status Epilepticus in Children; Risk Factors, Management and Early Outcome

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2008
Introduction: Refractory status epilepticus is a life-threatening disease in children wherein seizure movements don't response to first line anti convulsion drugs. This study reviewed risk factors, management and early outcome of children with refractory
AH Jafari Roohi, M Barzegar
doaj  

Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects [PDF]

, 2012
Temporal lobe epilepsy is a common, chronic neurological disorder characterized by recurrent spontaneous seizures. MicroRNAs (miRNAs) are small, noncoding RNAs that regulate post-transcriptional expression of protein-coding mRNAs, which may have key ...
A Pavlowsky, A Pitkänen, A Pitkänen, A Vezzani, B Lee, BM Murphy, C Brandt, CH Kim, CM O'Tuathaigh, Colm O'Tuathaigh, David C Henshall, DH Bhatt, Donncha F O'Brien, DP Bartel, DP Wermeling, E Aronica, EM Jimenez-Mateos, EM Jimenez-Mateos, EM Jimenez-Mateos, Eva M Jimenez-Mateos, FV Karginov, G Mouri, G Sierra-Paredes, Genshin Mouri, GM Schratt, I Ballesteros-Yáñez, J DeFelipe, J Elmén, J Gao, J Krützfeldt, J Krützfeldt, J Nairismägi, J Noguchi, J Tao, J Wetherington, JA Saugstad, Javier DeFelipe, JE Cavazos, JO McNamara, John L Waddington, K Hu, Katsuhiro Tanaka, KL Stark, L Peters, LH Zeng, M Christensen, M Lagos-Quintana, M Matsuzaki, M Müller, M Segal, Michael A Farrell, N Rensing, Norman Delanty, P Merino-Serrais, P Penzes, Paula Merino-Serrais, Q Zhou, R Meller, Raymond L Stallings, Ronán M Conroy, Ross C McKiernan, S Halpain, S Shinoda, SM Eacker, Suzanne Prenter, T Araki, T Engel, T Engel, T Saneyoshi, Takanori Sano, Tobias Engel, UV Nägerl, V Ambros, Y Meng, YJ Song   +74 more
core   +3 more sources

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Treatment of Status Epilepticus [PDF]

Journal of Neurocritical Care, 2016
Status epilepticus is a severe neurological disease associated with substantial mortality and health-care cost. Treatment of status epilepticus should proceed without delay even in the pre-hospital setting because prolonged generalized convulsive ...
Gha-Hyun Lee, Dae Soo Jung
doaj   +1 more source