Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Refrigerant and Oil Migration and Retention in Air Conditioning and Refrigeration Systems [PDF]
Air Conditioning and Refrigeration Project ...
Newell, T.A., Sheth, V.P.
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The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
The Analysis of Next-Generation Refrigerants in Terms of Energy, Exergy, and LCCP Perspective
In this study, commonly used hydrofluorocarbon (HFC)-based refrigerants R404A and R410A, as well as hydrofluoroolefin (HFO)-based environmentally friendly next-generation refrigerant R1234yf with a low global warming potential (GWP), were analyzed in ...
Mehmet Onur Karaagac +3 more
doaj +1 more source
Optimization of Heat Exchanger Design Parameters for Hydrocarbon Refrigerant Systems [PDF]
Hydrocarbon refrigerants (HC's) are one alternative to hydrofluorocarbons (HFC???s) since they have zero ozone depletion potential and negligible global warming potential.
Bullard, C.W., Jain, S.
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SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Carbon Dioxide Heat Transfer Coefficients And Pressure Drops During Flow Boiling: Assessment Of Predictive Methods [PDF]
Among the alternatives to the HCFCs and HFCs, carbon dioxide emerged as one of the most promising environmentally friendly refrigerants. In past years many works were carried out about CO2 flow boiling and very different two-phase flow characteristics ...
A. Rosato +3 more
core +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
Flame Suppression Effects of Binary Extinguishants on the Flammability of HFO-1243zf
HFO-1243zf (R1243zf) is a refrigerant with a low global warming effect and high development potential. The safety classification of R1243zf is A2; therefore, its flammability cannot be ignored.
Wu Xi +4 more
doaj
Engineering design project : series 2 [PDF]
This book is a compilation of engineering design projects which illustrates a detail explanation on the design process including all tools and methods involved in each design stage.
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