Results 41 to 50 of about 10,659 (309)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Effect of cross-sectional geometry on the compression fatigue behavior of NiTi refrigerants

AIP Advances, 2022
Elastocaloric refrigeration requires refrigerants with a good heat transfer ability and a high fatigue life. A million-level fatigue life can be normally obtained for NiTi refrigerants via compressive loading.
Guoan Zhou, Lingyun Zhang
doaj   +1 more source

An overview of refrigeration and refrigeration cycles

, 2020
Refrigeration is a process of keeping a system or surroundings at a temperature lower than ambient temperature. It has many advantages. It helps in keeping bodies at lower temperature so that it does not perish. Also it gives cooling effect during summer when ambient temperature is high. There are many ways or processes refrigeration can be done.
openaire   +2 more sources

Low-GWP Refrigerants: The Importance of the Thermophysical Properties for HVAC Design

, 2022
openNovel refrigerants with short atmospheric lifetime are being investigated to replace previous generations of working fluids in refrigeration, air-conditioning, and heat pump systems.
GRESELIN, IVAN
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Natural refrigerants versus synthetic refrigerants for steam-generating heat pumps

, 2022
Industrial heat pumps supplying steam at saturation temperatures up to 200°C are an emerging technology, which can help replacing fossil-fuel driven boilers. For these temperatures, little research is performed on refrigerant selection.
Arteconi, Alessia, Abedini, Hamed, Lecompte, Steven, Demeester, Toon, Vieren, Elias, Beyne, Wim, De Paepe, Michel   +6 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Evaluation of HFE-73DE/Ethyl Acetate Mixtures for Use in Minichannel Heat Exchangers

Energies
Binary mixtures of HFE-73DE and ethyl acetate are investigated as dielectric working fluids for laminar minichannel cooling. Thermophysical properties of the pure components and four mixtures (10/90, 25/75, 50/50 and 75/25 mass % HFE-73DE/ethyl acetate ...
Artur Piasecki, Beata Maciejewska, Magdalena Piasecka, Mirosław Grabowski, Paweł Grabowski   +4 more
doaj   +1 more source

Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies

Advanced Engineering Materials, EarlyView.
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo, Daniela Winsley Valereto Friozi, Vinícius de Oliveira, Marcia Cristina Branciforti   +3 more
wiley   +1 more source

Fostering Innovation: Streamlining Magnetocaloric Materials Research by Digitalization

Advanced Engineering Materials, EarlyView.
Magnetocaloric cooling (MCE) is an environmentally friendly refrigeration method with great potential. Optimizing MCE materials involves the preparation and screening of large quantities of samples, which in turn generates a large amount of data. A digitalization approach is presented that uses ontologies, knowledge graphs, and digital workflows to ...
Simon Bekemeier, Moritz Blum, Luana Caron, Alisa Chirkova, Philipp Cimiano, Basil Ell, Inga Ennen, Michael Feige, Maik Gaerner, Thomas Hilbig, Andreas Hütten, Günter Reiss, Tapas Samanta, Sonja Schöning, Christian Schröder, Lennart Schwan, Chris Taake, Martin Wortmann   +17 more
wiley   +1 more source