Results 101 to 110 of about 193,388 (229)
Inhaled Angiopoietin‐Like 4 Antisense Oligonucleotide Therapy for Lung Injury and Fibrosis
Advanced Science, EarlyView.Inhaled antisense oligonucleotides targeting ANGPTL4 attenuate inflammation, preserve barrier integrity, and reduce fibrosis in both infectious and sterile lung injury models. Integrated transcriptomic analysis reveals a conserved ANGPTL4‐regulated gene network coordinating hypoxic, inflammatory, apoptotic, and stress‐response pathways.
Haiyang Fan +21 more
wiley +1 more source
New nut and sleeve improve flared connections [PDF]
, 1965 Improved nut and sleeve of standard stainless steel flared tube connection allows forces on the mating surfaces to be uniformly applied. This can be applied to pressurized fluid systems such as refrigeration, air conditioning, and hydraulic ...
Garrard, J. S.
core +1 more source
A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis
Advanced Science, EarlyView.This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou +14 more
wiley +1 more source
An experimental study for a miniature Stirling refrigerator [PDF]
Experimental results of a miniature two-stage Stirling cryocooler are introduced. The influence of filling gas pressure and refrigeration temperature on the refrigerating capacity along with the relationship between parameters was measured.
Chen, G. +5 more
core +1 more source
Fill and vent quick disconnect [PDF]
, 1972 Hydraulic disconnect coupling on ground serving half of spacecraft refrigeration cooling system employs movable center stem for venting and closing nipple poppet.
Boerner, R. Y., Hedrick, R. W.
core +1 more source
Advanced Science, EarlyView.Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao +36 more
wiley +1 more source
Safe transport of diborane in a dual refrigerant system: A concept [PDF]
, 1972 Mobile transport system, that can be carried by truck and parked in storage area, consists of an inner container capable of holding 363 kg of diborane and an external, dual refrigeration unit which uses liquid nitrogen and Freon ...
Stone, G. R.
core +1 more source
Advanced Science, EarlyView.This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou +8 more
wiley +1 more source
Electron cooling by diffusive normal metal - superconductor tunnel junctions
, 2009 We investigate heat and charge transport in NN'IS tunnel junctions in the diffusive limit. Here N and S are massive normal and superconducting electrodes (reservoirs), N' is a normal metal strip, and I is an insulator.
A. F. Andreev +15 more
core +3 more sources
Advanced Science, EarlyView.Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li +12 more
wiley +1 more source