Results 131 to 140 of about 164,576 (302)

4E analysis of a two-stage refrigeration system through surrogate models based on response surface methods and hybrid grey wolf optimizer. [PDF]

open access: yesPLoS One, 2023
Ahmed R   +8 more
europepmc   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

open access: yesAdvanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin   +12 more
wiley   +1 more source

Trackable Tolerogenic Macrophages Integrate PD‐L1 and Rapamycin Signaling to Suppress Alloimmune Responses in Transplantation

open access: yesAdvanced Science, EarlyView.
We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang   +14 more
wiley   +1 more source

Discussion of Energy Efficiency Calculation Critera in Integrated System Coupling Refrigeration with Heating

open access: yesZhileng xuebao, 2018
With the deepening of energy conservation and emission reduction, the improvement of energy efficiency, integrated system coupling refrigeration with heating is bound to be further promoted and applied.
Zhai Xiaoting   +5 more
doaj  

Helium-refrigeration system

open access: yes, 1995
The design, procurement, and preliminary construction was completed for adding two more wet expansion engines to two helium refrigerators. These will be added in mid-year FY 1995. In addition a variable speed drive will be added to an existing helium compressor.
J R Specht, B Millar, A Sutherland
openaire   +2 more sources

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

open access: yesAdvanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei   +17 more
wiley   +1 more source

Performance Analysis on a Solar-powered Air-cooled Two-stage Ejector Refrigeration System with Ammonia as Refrigerant at Cold Storage

open access: yesZhileng xuebao, 2011
By the establishment of a mathematical model on a solar-powered air-cooled two-stage ejector refrigeration system using ammonia as refrigerant,the performance of ejector refrigeration system with rated refrigeration capacity of 9.4kW for cold store was ...
doaj   +2 more sources

Comprehensive evaluation on a combined refrigeration system of producing dry ice storage cold using fluctuating liquefied natural gas cold energy

open access: yesInternational Journal of Air-Conditioning and Refrigeration
In view of the fluctuations in the LNG regasification rate caused by the use of NG, in order to effectively utilize the unstable LNG cold energy, a combined refrigeration system utilizing the unstable LNG cold energy for producing dry ice storage cold is
Jinghong Ning   +4 more
doaj   +1 more source

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