Results 91 to 100 of about 177,895 (311)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Environmental sanitation conditions and health impact: a case-control study

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2003
This epidemiological investigation examines the impact of several environmental sanitation conditions and hygiene practices on diarrhea occurrence among children under five years of age living in an urban area.
Léo Heller   +2 more
doaj  

A plan development process for solid and hazardous waste management in the Manawatu-Wanganui region: a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy at Massey University [PDF]

open access: yes, 1992
This thesis uses elements of the strategic and integrated planning process models to develop a planning process for solid and hazardous waste management for use by a New Zealand regional council.
Robson, Bridget
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Application of Geographic Information Systems for Flood Risk Analysis: A Case Study from Accra Metropolitan Area

open access: yesPresent Environment and Sustainable Development, 2019
The main objective of the study was to identify high flood risk zones in AMA. The study also used questionnaires to assess local knowledge on what accounts for the high flood risk in their community.
Owusu Alex Barimah, Agbozo Mathias
doaj   +1 more source

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

Controle dos resíduos sólidos com envolvimento de população de baixa renda The involvement of low-income population in the control of solid waste

open access: yesRevista de Saúde Pública, 1990
Tendo em vista a melhora de condições de saúde em uma favela da cidade de São Paulo, Brasil, foram realizados dois estudos sobre a alteração de comportamento relacionados à coleta e triagem do lixo, com participação ativa da população.
José Luiz Crivelatti de Abreu
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Solid medical waste: a cross sectional study of household disposal practices and reported harm in Southern Ghana

open access: yesBMC Public Health, 2017
Background Solid medical waste (SMW) in households is perceived to pose minimal risks to the public compared to SMW generated from healthcare facilities.
Emilia Asuquo Udofia   +2 more
doaj   +1 more source

Solid Wastes, Poverty and the Environment in Developing Country Cities [PDF]

open access: yes
Many cities in Africa, Asia, and Latin America face serious problems managing their wastes. Two of the major problems are the insufficient collection and inappropriate final disposal of wastes.
Medina, Martin
core  

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