Results 61 to 70 of about 566,103 (339)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Nine circular strategy approach for the sustainable management of waste in the palm oil industry [PDF]

Global Journal of Environmental Science and Management
BACKGROUND AND OBJECTIVES: Only a tiny portion of the fresh palm oil fruit harvested can be converted into oil products. The majority of the harvested produce is discarded, indicating that it has not been utilized to its fullest potential.
S. Suprihatin, N.S. Indrasti, H. Prasetya, L. Agustina, E. Yulistika   +4 more
doaj   +1 more source

Tenement House Conditions in Five Rhode Island Cities [PDF]

, 1911
George H. Webb, Commissioner. Carol Aronovici, Special Agent. Rhode Island Bureau of Industrial Statistics. Part I of the Annual Report for 1910. A report commissioned by the Rhode Island Bureau of Industrial Statistics conducted in cooperation with ...
Aronovici, Carol, Webb, George H.
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Minimum quantity of urban refuse compost affecting physical and chemical soil properties

Italian Journal of Agronomy, 2006
The increasing production of urban waste requires urgent responses because of various environmental problems that arise when urban refuse is stored in landfills or incinerated.
Paolo Bazzoffi, Sergio Pellegrini, Andrea Rocchini   +2 more
doaj   +1 more source

Grazing to Gravy: Faunal Remains and Indications of Genízaro Foodways on the Spanish Colonial Frontier of New Mexico [PDF]

, 2017
Understanding identity aspects of those labeled Genízaro during the late Spanish Colonial period of New Mexico benefits from finer-grained perspectives on what ranges and mixtures of practices persons bearing this casta designation may have performed ...
Sunseri, JU
core   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Factors Influencing Outbreak of Diarrhoea among Children under the age of five years in Borno State

Ibom Medical Journal
Introduction: Diarrhoea infection has been recognized as one of the world’s leading causes of morbidity and mortality, resulting in over two million deaths per year, especially children in resource-limited countries Aim: To assess the factors ...
Lola N, Kever RT, Hamina D, Alhaji A
doaj   +1 more source

Vertical Distribution of Cadmium and Lead on Soils Affected by Metropolitan Refuse Disposal in Owerri, Southeastern Nigeria [PDF]

Iranica Journal of Energy and Environment, 2011
The authors investigated distribution of cadmium (Cd) and lead (Pb) in soil profile pits affected by municipal solid wastes in Avu dumpsite in Owerri, Southeastern Nigeria in 2010.
E.U. Onweremadu, J.U. Amaechi, B.N. Ndukwu   +2 more
doaj  

Características químicas do lixo de formigueiros de Atta sexdens rubropilosa (Hymenoptera: Formicidae) mantidos com diferentes substratos Chemical characteristics of nest refuse of Atta sexdens rubropilosa (Hymenoptera: Formicidae) reared with different substrates

Revista Brasileira de Ciência do Solo, 2007
As saúvas (Atta spp.) estão amplamente distribuídas pelo continente Sul-Americano e são consideradas importantes componentes do ecossistema neotropical. Diversos estudos têm demonstrado o efeito de formigueiros no enriquecimento do solo e na facilitação ...
Marcelo Braga Bueno Guerra, Carlos Ernesto G.R. Schaefer, Leandro Sousa-Souto   +2 more
doaj   +1 more source