Results 171 to 180 of about 1,397,234 (360)

Biomimetic Design of Biocompatible Neural Probes for Deep Brain Signal Monitoring and Stimulation: Super Static Interface for Immune Response‐Enhanced Contact

open access: yesAdvanced Functional Materials, EarlyView.
Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong   +7 more
wiley   +1 more source

HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington’s disease mice

open access: yesCell Death and Disease
Huntington’s disease (HD) is a monogenic neurodegenerative disease, caused by the CAG trinucleotide repeat expansion in exon 1 of the Huntingtin (HTT) gene. The HTT gene encodes a large protein known to interact with many proteins.
Laiqiang Chen   +13 more
doaj   +1 more source

Education for Regeneration [PDF]

open access: yes, 2016
It seems to me that we must think in terms of regeneration and resurgence, as Simpson says, not mere sustainability. Following centuries of colonization and imperialism, industrial “development”, toxic pollution, and carbon emissions from burning fossil ...
Perkins, Patricia E. (Ellie)
core  

Dynamic Micromechanical Characterization of 3D Printed Bone In Vitro Models Manufactured via Vat Photopolymerization

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a novel approach to designing and fabricating high‐porosity 3D‐printed scaffolds using a customized resin. Scaffold geometry, cellular interactions, and mechanical properties are analyzed to demonstrate these engineered bone models.
Sera Choi   +6 more
wiley   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

open access: yesAdvanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu   +6 more
wiley   +1 more source

Material Composition Gradient Controls the Autonomous Opening of Banksia Seed Pods in Fire‐Prone Habitats

open access: yesAdvanced Functional Materials, EarlyView.
The seed pod valves of Australian Banksia attenuata plants are not simply bi‐layers which bend when dry. These experiments and models reveal complex mechanics, which allow seed release only after several steps of seed pod opening. Stiffness gradients prevent delamination of the valves during loading, and a shape‐memory function protects the seeds ...
Friedrich Reppe   +7 more
wiley   +1 more source

Highly Coordinated Gene Regulation in Mouse Skeletal Muscle Regeneration [PDF]

open access: yes, 2003
Mammalian skeletal muscles are capable of regeneration after injury. Quiescent satellite cells are activated to reenter the cell cycle and to differentiate for repair, recapitulating features of myogenesis during embryonic development.
Choi, Sangdun   +9 more
core   +1 more source

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