Results 121 to 130 of about 190,601 (304)

A cut-off value for endothelial dysfunction based on the triglyceride-glucose index

Scientific Reports
We defined triglyceride-glucose (TyG) index 
Takayuki Yamaji, Farina Mohamad Yusoff, Shinji Kishimoto, Masato Kajikawa, Takahiro Harada, Aya Mizobuchi, Shunsuke Tanigawa, Tatsuya Maruhashi, Yukiko Nakano, Yukihito Higashi   +9 more
doaj   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

A dual platform approach to transcript discovery for the planarian Schmidtea mediterranea to establish RNAseq for stem cell and regeneration biology

, 2010
The use of planarians as a model system is expanding and the mechanisms that control planarian regeneration are being elucidated. The planarian Schmidtea mediterranea in particular has become a species of choice.
Rowsell Joanna, A Aziz Aboobaker, Kao Damian, Virginie Lemay, Sabrina Lam, Lemay, V, Wilson, R, Rowsell, J, Martin J Blythe, Jamie Jowett, Aboobaker A. Aziz, Damian Kao, Lam, S, Evans, D, Jowett, J, Sunir Malla, A. Aziz Aboobaker, Blythe Martin J., Evans Deborah, Lemay Virginie, Lam Sabrina, Kao, D, Malla, S, Ray Wilson, Aboobaker, Aziz, Wilson Ray, Jowett Jamie, Blythe, MJ, Malla Sunir, Deborah Evans, Hall Amy, Martin J. Blythe, Hall, A, Joanna Rowsell, Amy Hall   +34 more
core   +2 more sources

Use of Lectins to Enrich Mouse ES-Derived Retinal Progenitor Cells for the Purpose of Transplantation Therapy

Cell Transplantation, 2010
Using the mouse ES cell line with green fluorescent protein knocked-in at the Rx locus (Rx-KI ES cell), we previously showed that photoreceptors can be efficiently obtained in defined culture conditions by enriching Rx-positive retinal progenitor cells ...
Michiko Mandai, Hanako Ikeda, Zi-Bing Jin, Kyoko Iseki, Chie Ishigami, Masayo Takahashi   +5 more
doaj   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

The Effects of Betadine®, Polyvinylpyrrolidone (PVP), and Iodine on Regeneration in the Planarian \u3cem\u3eDugesia tigrina\u3c/em\u3e.

, 2010
The freshwater planarian has a great capacity to regenerate and is an ideal animal model in the study of stem cell and regeneration biology. In this study planarian regenerating new tails were exposed to nonlethal doses of Betadine®, Polyvinylpyrrolidone
Shaffer, Traci R
core  

LEC2 induces somatic cell reprogramming through epigenetic activation of plant cell totipotency regulators

Many plant species can develop embryos from somatic cells without fertilization. During this process, known as somatic embryogenesis, changes in the DNA methylation patterns are characteristic of reprogramming somatic cells into an embryogenic state ...
Li Ping Tang, Su, Ying Hua, Zhang, Qi, Ying Hua Su, Biao Jie Xu, Qi Zhang, Jing Peng, Zhang, Xian Sheng, Peng, Jing, Tang, Li Ping, Thomas Laux, Laux, Thomas, Xu, Biao Jie, Xian Sheng Zhang   +13 more
core   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

Harnessing beta cell regeneration biology for diabetes therapy

Trends in Endocrinology & Metabolism
The pandemic scale of diabetes mellitus is alarming, its complications remain devastating, and current treatments still pose a major burden on those affected and on the healthcare system as a whole. As the disease emanates from the destruction or dysfunction of insulin-producing pancreatic β-cells, a real cure requires their restoration and protection.
Stephanie Bourgeois, Sophie Coenen, Laure Degroote, Lien Willems, Annelore Van Mulders, Julie Pierreux, Yves Heremans, Nico De Leu, Willem Staels   +8 more
openaire   +2 more sources

SoxC and MmpReg promote blastema formation in whole-body regeneration of fragmenting potworms Enchytraeus japonensis

Regeneration in many animals involves the formation of a blastema, which differentiates and organizes into the appropriate missing body parts.
Chihiro Mori, Naoya Aoki, Koichi J. Homma, Shinji Yamaguchi, Toshiyuki Fujita   +4 more
core   +1 more source