Results 201 to 210 of about 448,418 (302)

Drift of positional identity drives reproductive aging in a long-lived regenerative animal. [PDF]

Curr Biol
Verdesca A, Poulet A, Bales M, van Wolfswinkel JC.   +3 more
europepmc   +1 more source

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

Advanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman, Hadas Oved, Itay Gil, Amgad Marzook, Ester Sapir Baruch, Yahel Shechter, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

SHED secretome hydrogel combined with α-mangostin for periodontal bone regeneration: In vivo study. [PDF]

J Oral Biol Craniofac Res
Aljunaid MA, Ridwan RD, Budi HS, Yuliati, Qaid HR, Mahendra RD, Riveira CM, Aqrabi AN, Putranto AF, Al-Ghazaly F, Al-Kawri OM.   +10 more
europepmc   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

<i>C. elegans</i> Spastin/<i>spas-1</i> Is Required for Axon Regeneration and Maintenance. [PDF]

eNeuro
Howell MC, El Bejjani RM.
europepmc   +1 more source

SULF1/SULF2 reactivation during liver damage and tumour growth [PDF]

, 2016
A Giakoustidis, A Schulze, AP Sahota, C Bret, CL Merry, D Shukla, DC Kroy, G Xu, G Zaman, GK Dhoot, GK Dhoot, Gurtej K. Dhoot, H Barth, H Lemjabbar-Alaoui, J Lai, Joshua I. Murphy, JP Lai, JP Lai, JP Lai, JWY Tuo, K Uchimura, Kurtis Graham, L Hitchins, M Ford-Perriss, M Meyers-Needham, M Morimoto-Tomita, M Tarocchi, MT Joy, P Tátrai, R Gill, R Nawroth, RB Gill, RB Gill, RM Gill, S Ashikari-Hada, S Wang, S Wang, SD Rosen, X Ai, X Ai, Y Xu, YC Kwon   +41 more
core   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source

Effect of Autologous Bioactive Concentrated Growth Factor and Residual Dental Pulp on Dentin-Pulp Complex Regeneration. [PDF]

Biomedicines
Wahba AE, Elwaseef S, Mostafa HI, Abdelhameed WB, Mostafa Abbas A, Emran AM.   +5 more
europepmc   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

DHEA inhibits regeneration in <i>Lumbriculus variegatus</i>. [PDF]

MicroPubl Biol
Frank E, Pardue I, Rahman I, Banthin E, Gillen K.   +4 more
europepmc   +1 more source