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Signaling pathways regulating the fate of fibro/adipogenic progenitors (FAPs) in skeletal muscle regeneration and disease

The FEBS Journal, 2021
The characterization of fibro/adipogenic progenitor cells (FAPs) in the skeletal muscle has contributed to modify the monocentric view of muscle regeneration beyond muscle satellite cells (MuSCs).
G. Giuliani, M. Rosina, A. Reggio
semanticscholar   +1 more source

Somatic Stem Cell Biology and Periodontal Regeneration

The International Journal of Oral & Maxillofacial Implants, 2013
Somatic stem cells have been acknowledged for their ability to differentiate into multiple cell types and their capacity for self-renewal. Some mesenchymal stem cells play a dominant role in the repair and reconstruction of periodontal tissues. Both dental-derived and some non-dental-derived mesenchymal stem cells possess the capacity for periodontal ...
Yan Jin, Dehua Li, Bin Zhu, Yihan Liu
openaire   +3 more sources

Biology of Cartilage Regeneration

2016
Hyaline articular cartilage is an avascular, low-friction, and wear-resistant weight bearing surface that has limited capacity for self-repair. The optimal treatment for cartilage lesions has yet to be established. Various treatment methods are employed to reestablish a stable cartilage surface, including microfracture, autologous and allograft ...
Cecilia Pascual-Garrido, Scott A. Rodeo
openaire   +2 more sources

Molecular and cell biology of skeletal muscle regeneration

1993
When skeletal muscle is damaged, it is repaired by the proliferation of mononuclear muscle precursor cells (mpc) which fuse either with one another to form young multinucleated muscle cells (myotubes) or with the ends of damaged myofibres (Robertson et al., 1990).
Miranda D. Grounds   +1 more
openaire   +3 more sources

Beyond Casual Resemblances: Rigorous Frameworks for Comparing Regeneration Across Species.

Annual Review of Cell and Developmental Biology, 2021
The majority of animal phyla have species that can regenerate. Comparing regeneration across animals can reconstruct the molecular and cellular evolutionary history of this process. Recent studies have revealed some similarity in regeneration mechanisms,
M. Srivastava
semanticscholar   +1 more source

Human Organoids: Tools for Understanding Biology and Treating Diseases.

Annual Review of Pathology, 2020
Organoids are in vitro-cultured three-dimensional structures that recapitulate key aspects of in vivo organs. They can be established from pluripotent stem cells and from adult stem cells, the latter being the subject of this review.
Frans Schutgens, H. Clevers
semanticscholar   +1 more source

Stem Cell Biology for Vascular Regeneration

2006
The isolation of endothelial progenitor cells (EPCs) derived from bone marrow (BM) was one epoch-making event for the recognition of neovessel formation in adults occurring as physiological and pathological responses. The finding that EPCs home to sites of neovascularization and differentiate into endothelial cells (ECs) in situ is consistent with ...
openaire   +3 more sources

In silicobiology of bone modelling and remodelling: regeneration

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2009
Bone regeneration is the process whereby bone is able to (scarlessly) repair itself from trauma, such as fractures or implant placement. Despite extensive experimental research, many of the mechanisms involved still remain to be elucidated. Over the last decade, many mathematical models have been established to investigate the regeneration processin ...
J. Vander Sloten   +2 more
openaire   +3 more sources

The Hippo Pathway: Biology and Pathophysiology.

Annual Review of Biochemistry, 2019
The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...
Shenghong Ma, Z. Meng, Rui Chen, K. Guan
semanticscholar   +1 more source

The Molecular Biology of Hair Cell Regeneration in the Avian Cochlea

Audiology and Neurotology, 1997
The sensory cells of the ear, the hair cells, are damaged by loud noise or certain types of drugs. In the bird cochlea, new hair cells are produced to replace those that are lost. Regeneration also occurs in the vestibular epithelia of birds, fish, and mammals but does not occur in the mammalian cochlea.
Kenneth H. Lee   +3 more
openaire   +3 more sources

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