Results 191 to 200 of about 50,563 (351)

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

open access: yesAdvanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia   +5 more
wiley   +1 more source

Simulation of An Electrocaloric Cooling Structure Based on Heat Regeneration

open access: green
Xiangrui Meng   +4 more
openalex   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

open access: yesAdvanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen   +13 more
wiley   +1 more source

Improved Two-Dimensional Kinetics (TDK) computer program [PDF]

open access: yes
Fluid properties, the boundary layer module, and regenerative cooling are discussed. Chemistry, low density flow effects, test cases, input and output for TDK, and documentation are also ...
Dang, L. D., Nickerson, G. R.
core   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

open access: yesAdvanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li   +9 more
wiley   +1 more source

Investigation of small-scale hydrazine- fluorine injectors [PDF]

open access: yes
Performance tests of shower-head, triplet, and like-on-like liquid hydrazine-fluorine injectors in uncooled rocket ...
Rollbuhler, R. J., Tomazic, W. A.
core   +1 more source

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