Results 71 to 80 of about 7,403 (309)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

CFD simulation of an industrial FCC regenerator [PDF]

open access: yes, 2016
Through a Computational Fluid Dynamics (CFD) simulation of the particle laden flow of the two stages of a Fluid Catalytic Cracking (FCC) High Temperature Regenerator (HTR), new designs for the particle distributor in the combustor stage and the arm ...
Alzate Hernández, Juan David
core  

CFD Analysis of Regenerative Chambers for Energy Efficiency Improvement in Glass Production Plants

open access: yesEnergies, 2015
The overall efficiency of a regenerative chamber for a glass furnace mainly relies on the thermo-fluid dynamics of air and waste gas alternatively flowing through stacks of refractory bricks (checkers) determining the heat recovery.
Davide Basso   +3 more
doaj   +1 more source

Cartilage Regeneration [PDF]

open access: yesJournal of the American Academy of Orthopaedic Surgeons, 2013
Cartilage damaged by trauma has a limited capacity to regenerate. Current methods of managing small chondral defects include palliative treatment with arthroscopic débridement and lavage, reparative treatment with marrow-stimulation techniques (eg, microfracture), and restorative treatment, including osteochondral grafting and autologous chondrocyte ...
Rocky S, Tuan   +2 more
openaire   +2 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

混合網目再生器的流力數值分析

open access: yes, 2023
The regenerator is the core heat exchange component of the Stirling refrigerator, and its performance is determined by the configurations and physical properties of the wire mesh.
Kumar, Kuttum Pavan;Gupta, Pratik Prakash;Senthilkumar, Sundararaj;Kang, Shung-Wen
core  

Numerical optimization of metal felt regenerators with axially varying matrix structures for Stirling engines

open access: yesInternational Journal of Thermofluids
The regenerator is the crucial component for the performance of any regenerative gas cycle. Due to the changing gas properties and flow conditions in the axial direction of a regenerator, a variation of its parameters in that direction is a promising ...
Sebastian Peveling, Hans-Detlev Kühl
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Development of parallel wire regenerator for cryocoolers

open access: yes, 2006
This paper describes development of a novel regenerator geometry for cryocoolers. Parallel wire type is a wire bundle stacked in parallel with the flow in the housing, which is similar to a conventional parallel plate or tube.
Jeong, Sangkwon, Nam, K
core   +1 more source

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