Results 241 to 250 of about 953,394 (306)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

On the origin of acoustic emission in the stress-induced martensite regime of shape memory alloys. [PDF]

Nat Commun
Lauhoff C, Weidner A, Lehnert R, Reul A, Pham T, Gutmann MJ, Krooß P, Schmahl WW, Biermann H, Seiner H, Niendorf T.   +10 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

General inverse-cube thickness scaling of projectile penetration energy in ultrathin films. [PDF]

Proc Natl Acad Sci U S A
Zaccone A, Sirk TW.
europepmc   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Yield-quality relationships under deficit irrigation in greenhouse tomato: modulation by seaweed biostimulants. [PDF]

Front Plant Sci
Tringovska I, Marovska G, Velichkov G, Stoeva V, Atanasova V, Dobrev D, Ganeva D, Grozeva S.   +7 more
europepmc   +1 more source

Impact of light-matter coupling strength on the efficiency of microcavity OLEDs: a unified quantum master equation approach.

Mater Horiz
Siltanen O, Luoma K, Daskalakis KS.
europepmc   +1 more source

Meniscus-Mediated Imaging of Soft Biological Membranes Using 200 kN/m Ultra-Stiff 15 MHz MEMS AFM Probes. [PDF]

J Mol Recognit
Subramanian S, Mauran N, Casuso I, Legrand B.   +3 more
europepmc   +1 more source

Interface States in Space-Time Photonic Crystals: Topological Origin, Propagation, and Amplification. [PDF]

ACS Photonics
Caballero A, Allard TF, Huidobro PA.
europepmc   +1 more source

Decoupled phenotypic constraints framed by respiratory adaptation in the rise of land vertebrates. [PDF]

Sci Adv
Yu Y, Xu X, Benson RBJ.
europepmc   +1 more source