Results 21 to 30 of about 728,324 (311)

Difficulties in managing patients with hepatolenticular degeneration

Анналы клинической и экспериментальной неврологии, 2018
In this paper, we present some typical problems of managing patients with hepatolenticular degeneration (HLD), a severe hereditary disorder of cupper metabolism requiring permanent cupper-eliminating therapy.
Tatyana N. Proskokova, Nadezhda V. Vyalova, Natal'ya B. Serdyuk, Aleksandr M. Khelimsky   +3 more
doaj   +1 more source

Treatment outcome of multidrug-resistant tuberculosis with modified DOTS-plus strategy: A 2 years' experience

Lung India, 2019
Background: Multidrug-resistant tuberculosis (MDR-TB) is a global health problem with notoriously difficult and challenging treatment. This study determined treatment outcome in patients of MDR-TB with modified DOTS-Plus strategy.
Abhijeet Singh, Rajendra Prasad, Ram Awadh Singh Kushwaha, Rahul Srivastava, Belur Hosmane Giridhar, Viswesvaran Balasubramanian, Amita Jain   +6 more
doaj   +1 more source

Characterization of the anti-AChE potential and alkaloids in Rhizoma Coptidis from different Coptis species combined with spectrum-effect relationship and molecular docking

Frontiers in Plant Science, 2022
Coptis species are the main source of Rhizoma Coptidis (RC) drugs, which have always been used to treat Alzheimer’s disease in the clinical experience of ancient China. However, many species of this genus have been largely underutilized until now.
Luming Qi, Luming Qi, Furong Zhong, Nannan Liu, Nannan Liu, Jie Wang, Jie Wang, Kaidi Nie, Kaidi Nie, Youli Tan, Yuntong Ma, Lina Xia, Lina Xia   +12 more
doaj   +1 more source

Dosage regimen design

Pharmacology & Therapeutics, 1982
Pharmacology and Therapeutics 17 (1982) 143-163. doi:10.1016/0163-7258(82)90009-2 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:21:19 ; DOI:10.1016/0163-7258(82)90009-2 ; Page Range: 143 ...
Division of Clinical Pharmacokinetics, College of Pharmacy, University of Florida, Gainesville, FL 32610, U.S.A. ( host institution ), Lindsay DeVane, C. ( author ), Jusko, William J. ( author )   +2 more
openaire   +3 more sources

High salt diet accelerates skin aging in wistar rats: an 8-week investigation of cell cycle inhibitors, SASP markers, and oxidative stress

Frontiers in Bioengineering and Biotechnology
BackgroundRecent studies have shown that the high salt diet (HSD) is linked to increased dermal pro-inflammatory status and reduced extracellular matrix (ECM) expression in inflamed skin of mice.
Xile Peng, Xile Peng, Xile Peng, Nannan Liu, Nannan Liu, Nannan Liu, Baihan Zeng, Baihan Zeng, Baihan Zeng, Yilin Bai, Yilin Bai, Yilin Bai, Yang Xu, Yang Xu, Yang Xu, Yixiao Chen, Yixiao Chen, Yixiao Chen, Li Chen, Li Chen, Li Chen, Lina Xia, Lina Xia, Lina Xia   +23 more
doaj   +1 more source

Effects of Health Qigong Exercise on Lower Limb Motor Function in Parkinson's Disease

Frontiers in Medicine, 2022
PurposeThis study explored the effects of Health Qigong exercise on lower limb motor function in patients with Parkinson's disease (PD).Patients and MethodsA total of 40 patients with PD were recruited and randomly allocated into the experimental group ...
Xiying Li, Chuanfen Lv, Xiaolei Liu, Xia Qin   +3 more
doaj   +1 more source

Role of potential bioactive metabolites from traditional Chinese medicine for type 2 diabetes mellitus: An overview

Frontiers in Pharmacology, 2022
Type 2 diabetes mellitus (T2DM) is a metabolic disease with persistent hyperglycemia primarily caused by insulin resistance (IR). The number of diabetic patients globally has been rising over the past decades.
Xiang Li, Jia-Jia Geng-Ji, Yun-Yun Quan, Lu-Ming Qi, Qiang Sun, Qun Huang, Hai-Mei Jiang, Zi-Jian Sun, Hong-Mei Liu, Xin Xie   +9 more
doaj   +1 more source

Compression fractures of the spine in children: isn’t it time to change something?

Хирургия позвоночника, 2019
Objective. To analyze the efficacy of various methods for treatment of children with compression fractures of the thoracic and lumbar spine on the basis of literature data. Material and Methods. A systematic review of the literature on methods for the
Nikita O. Khusainov, Sergey V. Vissarionov   +1 more
doaj   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Association between composite dietary antioxidant index and hyperlipidemia in adults based on the NHANES

Scientific Reports
Hyperlipidemia, a major risk factor for cardiovascular diseases, can potentially be alleviated by dietary antioxidants. This study explored the relationship between hyperlipidemia and the Composite Dietary Antioxidant Index (CDAI), which measures ...
Kaidi Nie, Tingting Deng, Yiling Bai, Yuxian Zhang, Zhixuan Chen, Xile Peng, Lina Xia, Jiao Liu   +7 more
doaj   +1 more source