Results 81 to 90 of about 699,410 (260)
Mistrust and social hierarchies as blind spots of ICT4D projects
TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2019 Information and communication technologies for development (ICT4D) are seen to have great potential for boosting democratization processes all over the world by giving people access to information and thereby empowering them to demand more accountability
Roos Keja, Kathrin Knodel
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Exchange rate regimes and trade [PDF]
A ‘new version’ gravity model, is used to estimate the effect of a full range of de facto exchange rate regimes, as classified by Reinhart and Rogoff (2004), on bilateral trade. The results indicate that, while participation in a common currency union is
David Cobham, Christopher Adam
core
Authoritarianism in the 21st Century
Politics and Governance, 2018 This introduction offers an overview of the key works in this edited volume on authoritarian regimes. This edited volume explains how authoritarian regimes were studied in the past and how this may contrast with how authoritarian regimes are studied ...
Natasha Ezrow
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2018 This paper argues for more complex analyses of welfare state gender regimes by focusing on a key element frequently forgotten in cross-national comparisons: intimate partner violence (IPV) and responses thereto, especially criminal justice system (CJS ...
Hearn, Jeff, +2 more
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Choice of exchange rate regimes for African countries: Fixed or Flexible Exchange rate regimes? [PDF]
The choice of an appropriate exchange rate regime has been a subject of ongoing debate in international economics. The majority of African countries are small open economies and thus where the choice of the exchange rate regime is an important policy ...
Simwaka, Kisu
core
Welfare Regimes in the UE 15 and in the Enlarged Europe: An exploratory analysis [PDF]
The basic aim of this paper is to assess existing welfare regimes in the countries of European Union before and after the enlargement of May 2004 (EU 15 and EU 25) building on a comprehensive approach that considers different dimensions of welfare ...
Adelaide Figueiredo +1 more
core +2 more sources