Results 61 to 70 of about 4,021,222 (313)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Manifiesto de Historia a Debate

open access: yesHistoria Regional, 2003
(No se dispone)
Comité Editorial Historia Regional
doaj  

PEREMPUAN DAN POLITIK LOKAL (STUDI KASUS PEMILIHAN KEPALA DAERAH DI SULAWESI TENGGARA)

open access: yesAl-Izzah, 2019
This qualitative study aimed to investigate the existence of women’s contestation in the local election in South East Sulawesi and to identify the female candidates’ effort to win the electoral competition.
Hadi Machmud
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

La represión contra los indígenas del Cauca

open access: yesRevista Controversia, 1979
El documento del CRIC presenta vívidamente la represión multiforme y concreta de que este movimiento ha sido víctima en los últimos años y analiza a través de hechos históricos las causas de esa represión, bajo el “Estado de Seguridad”.
CRIC Consejo Regional Indígena
doaj  

Minimum effective concentration 90 (EC90) of ropivacaine for Femoral nerve block: A biased-coin up-and-down sequential method study

open access: yesIndian Journal of Anaesthesia
Background and Aims: The femoral nerve (FN) is commonly blocked using ropivacaine to provide postoperative analgesia after knee surgery. However, the minimal required concentration has not yet been defined.
Ahmed M. Taha   +5 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Employers’ perspectives on recruiting and retaining pharmacists in regional and rural Victoria, Australia

open access: yesRural and Remote Health
Introduction: Pharmacies and pharmacists play an integral role in primary health care. This role is particularly important in regional and rural settings where workforce is scarce.
Zikai He, Lisa Bourke
doaj   +1 more source

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