Results 51 to 60 of about 4,345,063 (220)
Mechanizmy kontroli wykorzystania środków Unii Europejskiej w perspektywie finansowej 2014-2020
Prace Naukowe Uniwersytetu Ekonomicznego we Wrocławiu, 2019 The aim of control mechanisms is to verify if beneficiaries have fulfilled the conditions of a project financing agreement and separate accounting and financial reporting standards for these funds.
Alina Walenia
doaj
REGIONAL DISPROPORTIONS AND FISCAL ASYMMETRY IN UKRAINE UNDER MARTIAL LAW
Three Seas Economic JournalThe purpose of the paper is to provide a comprehensive quantitative assessment and scientific-methodological substantiation of the scale of spatial fiscal asymmetry in Ukraine under martial law, alongside developing applied, adaptive recommendations for
Oksana Vidomenko
doaj +1 more source
Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency
Advanced Science, EarlyView.How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen +10 more
wiley +1 more source
Advanced Science, EarlyView.Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang +4 more
wiley +1 more source
Advanced Science, EarlyView.Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao +19 more
wiley +1 more source
Environmental Research Letters, 2013 Globally, agriculture is directly responsible for 14% of annual greenhouse gas (GHG) emissions and induces an additional 17% through land use change, mostly in developing countries (Vermeulen et al 2012).
T S Rosenstock +3 more
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New Quality of the Accounting Chamber of Ukraine: Development Strategy [PDF]
: The international approaches to strategic planning in supreme audit institutions and current experience of European countries in developing such strategies are explored. The challenges and problems o f external audit in Ukraine are defined in
V. Nevidomyi Accounting Chamber of Ukraine, Kyiv, Ukraine +1 more
core
Advanced Science, EarlyView.In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang +11 more
wiley +1 more source
Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
Advanced Science, EarlyView.This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
Advanced Science, EarlyView.The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English +9 more
wiley +1 more source