Results 91 to 100 of about 4,944,391 (290)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Productivity Measurement: The Case of Nature Tourism Firms in Portugal [PDF]

Journal of Spatial and Organizational Dynamics, 2020
Productivity measurement in the tourism sector has been raising increasing interest among researchers and is recognised as an important indicator for understanding the strengths and weaknesses of the sector and for enhancing its spillover effects on the ...
Eleonora Santos, Alexandra I. Correia, Fernanda A. Ferreira, Alcina Maria Nunes, Cláudia Miranda Veloso, Elvira Vieira, Goretti Silva, Manuel Fonseca, Paulo Carrança, Paula Odete Fernandes   +9 more
doaj  

REGIONAL INNOVATION SYSTEM FAILURES AND HIGHLIGHTS [PDF]

The systemic analysis of innovation conceives complex analytical frameworks, with intense socio-technological aspects of knowledge generation and encompasses a detailed analysis of system failures.
Sotiris Zygiaris
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Gastritis in Northeast India and North India: A regional comparison of prevalence and associated risk factors

Biomedical and Biotechnology Research Journal
Background: Gastritis is one of the most prevalent disorders affecting individuals. Helicobacter pylori infection, along with other factors such as lifestyle, gender, alcohol drinking, and smoking are causes of gastritis.
Akshita Mathur, Valentina Gehlot, Shweta Mahant, Sangitanjan Dutta, Asish Kumar Mukhopadhyay, Kunal Das, Rajashree Das   +6 more
doaj   +1 more source

Methodology of regional analysis of the Russian economic reseaerch market

Ekonomika Nauki, 2019
After the dissolution of the Soviet Union and the transition to a market economy model in Russia, there has been observed a rapid growth for market economic studies challenge in ranking of its three segments, such as the economists market, scientific ...
V. M. Moskovkin, X. Sun
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Spatial Aspects of Job Creation: Evidence from Western Germany [PDF]

This paper provides detailed information about spatial interactions in the job creation process in West German regional labor markets. We investigate spatial (auto-) correlations in the matching process of vacancies and unemployed, examine regional ...
Fahr, Rene, Uwe Sunde
core  

Social capital, industrial districts and regional unemployment in Italy [PDF]

, 2012
We consider the industrial districts “conductors” of social capital. Hence, we use the regional density of industrial districts to measure social capital and we analyse its impact on regional unemployment in Italy. By using regional data from the Italian
Andriani, Luca
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source