Results 121 to 130 of about 591,450 (353)

Multivariate Screening and Automated Clustering of Macrophage Immunoreactome to Nanoparticles and Photothermal Therapy

open access: yesAdvanced Science, EarlyView.
Predicting immune responses to treatments, including nanomedicines, with high throughput test is challenging due to the immunoreactome's complexity and plasticity. A predictive screening platform integrating pathway activation and gene profiling in macrophages has been developed as a versatile tool for designing effective immunotherapies.
Sonia Becharef   +12 more
wiley   +1 more source

Effects of simulated weightlessness on regional blood flow specifically during cardiovascular stress [PDF]

open access: yes
Significant changes in the cardiovasular system of humans and animals have been observed following exposure to prolonged periods of weightlessness during space flight.
Harrison, D. C.
core   +1 more source

COMPARATIVE EVALUATION OF REGIONAL PERIODONTIUM TISSUEHEMODYNAMICS IN PATIENTS WITH PHYSIOLOGICAL OCCLUSION AND DENTOALVEOLAR ANOMALIES

open access: yesКубанский научный медицинский вестник, 2015
The rheoperiodontography method was employed to estimate both qualitative and quantitative parameters in children and adolescents (aged 12-15) with physiological occlusion and dentoalveolar anomalies in order to analyze their periodontium hemodynamics ...
D. A. Domenyuk   +2 more
doaj  

Non‐Invasive Diagnosis of Chronic Myocardial Infarction via Composite In‐Silico‐Human Data Learning

open access: yesAdvanced Science, EarlyView.
This study presents a non‐invasive machine learning model to identify infarct regions in the left ventricle using cardiac strain data. By combining rodent‐based simulated data with limited human data, the model achieves high accuracy in predicting infarct size and location without the need for gadolinium contrast agents, offering a promising ...
Rana Raza Mehdi   +7 more
wiley   +1 more source

Targeting Cystine Metabolism in the Lung Cancer Environment Enhances the Efficacy of Immune Checkpoint Inhibition

open access: yesAdvanced Science, EarlyView.
The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu   +20 more
wiley   +1 more source

Magnetic resonance quantification of regional blood flow and oxygen delivery to the brain, gut, kidneys, and lower extremities in adolescents with a Fontan circulation compared to biventricular controls

open access: yesJournal of Cardiovascular Magnetic Resonance
: Background: Accumulation of progressive extracardiac disease is nearly universal for patients with single ventricle heart disease palliated to a Fontan circulation; however, etiologies are poorly understood.
Jennifer Romanowicz   +8 more
doaj  

Research of peripheral blood circulation in patients with local form of chronic osteomyelitis

open access: yesActa Biomedica Scientifica, 2013
Expressed asymmetry (54,8 ± 14,37 — 58 ± 6,54 %) of blood flow on the injured extremity was revealed at rheography of peripheral blood flow in all patients with shin bones fractures complicated with local form of chronic traumatic osteomyelitis. The most
S. N. Leonova   +2 more
doaj  

Exploring the utility of near-infrared spectroscopy in liver transplantation: insights and challenges

open access: yesClinical Transplantation and Research
Maintaining adequate tissue perfusion and oxygen delivery to the transplanted liver is critical for positive patient outcomes. Near-infrared spectroscopy (NIRS) has emerged as a promising tool for evaluating graft function in liver transplantation ...
Ravshan Ibadov   +6 more
doaj   +1 more source

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

open access: yesAdvanced Science, EarlyView.
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou   +11 more
wiley   +1 more source

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