Results 241 to 250 of about 616,798 (355)

Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases

Annals of Neurology, EarlyView.
Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich, Martin Brüne, John S. Allen, Nicole Bender, Emiliano Bruner, Jean‐Pierre Changeux, Corrado Cali, Olga Dolgova, Anne Grünewald, Geneviève Konopka, Peng Jin, Roger Lemon, Gilberto Levy, Pierre Magistretti, Markus J. Rantala, Kathleen S. Rockland, Roger Sullivan, Annie Swanepoel, Toshiki Uchihara, Katrin Amunts, Christopher G. Goetz   +20 more
wiley   +1 more source

Cerebrovascular autoregulation in hypoxia: quantitative insights from arterial spin labeling. [PDF]

Front Neurosci
Troudi Habibi A, Micaux J, Mauconduit F, Noulhiane M.   +3 more
europepmc   +1 more source

Epstein–Barr Virus, Lower Vitamin D, Low Sun Exposure, and HLA‐DRB1*1501 Risk Variant Share Common Epigenetic Pathways Leading to Multiple Sclerosis Onset

Annals of Neurology, EarlyView.
Objectives Multiple sclerosis (MS) onset risk factors include Epstein–Barr virus (EBV) indices (including host response), lower serum 25‐vitamin D (25(OH)D) levels, low sun exposure, and HLA‐DRB1*1501. The underlying molecular mechanisms are unclear. Here, we examined mediation through differential DNA methylation (DNAm) to better understand possible ...
Steve Simpson‐Yap, Ellen Morwitch, Samuel A. Tanner, Sarah M. Thomson, Alex Eisner, Rod A. Lea, Trevor J. Kilpatrick, Jeannette Lechner‐Scott, Rodney J. Scott, Alexandre Xavier, Vicki E. Maltby, Robyn M. Lucas, Bruce V. Taylor, Brett A. Lidbury, Simon A. Broadley, Ingrid van der Mei, Mehari Woldemariam Merid, Boris Novakovic, Richard Saffery, Anna Karin Hedström, Pernilla Stridh, Tomas Olsson, Maja Jagodic, Lars Alfredsson, Anne‐Louise Ponsonby, for the Ausimmune Investigator Group, Caron Chapman, Alan Coulthard, Keith Dear, Terry Dwyer, Trevor Kilpatrick, Robyn Lucas, Tony McMichael, Anne‐Louise Ponsonby, Bruce Taylor, Patricia Valery, Ingrid van der Mei, David Williams   +37 more
wiley   +1 more source

Regional blood flow signatures of opioidergic modulation of ketamine in major depressive disorder: a randomised crossover study

Jelen LA, O’Daly O, Zelaya FO, Stone JM, Young AH, Mehta MA.   +5 more
europepmc   +1 more source

Disruption of the Blood–Brain Barrier Predicts Progression of Cerebral Small Vessel Disease White Matter Hyperintensities

Annals of Neurology, EarlyView.
Objective The objective of this study was to test if blood–brain barrier (BBB) disruption, detected using dynamic susceptibility contrast (DSC) imaging, would predict progression of white matter hyperintensities (WMHs) over the subsequent year in patients with chronic cerebrovascular disease. Methods The study included patients with a history of stroke
Richard Leigh, Kyle C. Kern, Nae‐Yuh Wang, Rebecca F. Gottesman, Clinton B. Wright   +4 more
wiley   +1 more source

Simultaneous ¹³N-ammonia and gadolinium perfusion using integrated PET-MRI: diagnostic accuracy in coronary microvascular dysfunction. [PDF]

Front Med (Lausanne)
Wen R, Xie Q, Pan B, Ni M, Zhu X, Meng X, Wei Z, Wu X, Li D, Wang X.   +9 more
europepmc   +1 more source

Green Synthesis of Silver Nanoparticles: A Review of Polymer and Antimicrobial Drug Combinations for Enhanced Antimicrobial Applications

Advanced NanoBiomed Research, EarlyView.
Silver nanoparticles (AgNPs) synthesized using eco‐friendly green synthesis approaches exhibit remarkable antimicrobial activity and enhanced drug delivery potential. Polymer‐AgNPs conjugates further improve drug stability and targeted delivery, offering a multifunctional platform for biomedical applications.
Mukil Madhusudanan, Jian Zhang, Santosh Pandit, Priyanka Singh, Geum‐Jae Jeong, Fazlurrahman Khan, Ivan Mijakovic   +6 more
wiley   +1 more source

Harlequin Syndrome in Venoarterial ECMO and ECPELLA: When ECMO and Native or Impella Circulations Collide - A Comprehensive Review. [PDF]

Rev Cardiovasc Med
Torre DE, Pirri C.
europepmc   +1 more source

Multiplexed Cutaneous Wound Monitor for Point‐of‐Care Applications

Advanced NanoBiomed Research, EarlyView.
Wearable monitors are poised to transform wound care, easing healthcare burdens. These devices integrate sensors and wireless capabilities, enabling continuous, remote monitoring. This work showcases a flexible, wireless system‐on‐chip that tracks C‐reactive protein (CRP), interleukin‐6 (IL‐6), pH, and temperature.
Peter Francis Mathew Elango, Ganganath Perera, Mingjie Yang, Mei Xian Low, Ying Zhi Cheong, Bharath Babu Manjunath, Md. Ataur Rahman, Rajesh Ramanathan, Sharath Sriram, Shanmuga Sundar Dhanabalan, Madhu Bhaskaran   +10 more
wiley   +1 more source

Alleviation of symptoms and paradoxical brain perfusion shift in oral cenesthopathy: A retrospective neuroimaging study. [PDF]

Front Psychiatry
Umezaki Y, Motomura H, Nagamachi S, Toyofuku A, Tu TTH, Naito T.   +5 more
europepmc   +1 more source