Results 41 to 50 of about 1,051,374 (303)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Changes of the Arctic climate under the SRES B2 scenario conditions
Meteorologische Zeitschrift, 2005 In the framework of the Sonderforschungsbereich 512 ("Cyclones and the North Atlantic climate system"), regional climate simulations of a control period (nominally 1970-1979) and future Arctic climate (2070-2079) have been conducted with the regional ...
Susanne Pfeifer, Daniela Jacob
doaj +1 more source
A framework for modeling uncertainty in regional climate change [PDF]
, 2015 In this study, we present a new modeling framework and a large ensemble of climate projections to investigate the uncertainty in regional climate change over the United States (US) associated with four dimensions of uncertainty.
Gao, X +4 more
core
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Upscaling fluxes from towers to regions, continents and global scales using datadriven approaches [PDF]
, 2011 Quantifying the current carbon cycle of terrestrial ecosystems requires that we translate spatially sparse measurements into consistent, gridded flux estimates at the regional scale.
Davis, Kenneth J. +4 more
core +6 more sources
A spatial context-aware model for climate model data fusion
International Journal of Digital EarthAcquiring more accurate climate model data is crucial for conducting precise regional climate studies. Most studies use linear weighting methods or a single machine learning model fusing multiple climate model datasets to reduce uncertainty.
Jinyu Meng, Zengchuan Dong, Yongze Song
doaj +1 more source
Weight assignment in regional climate models [PDF]
Climate Research, 2010 An important new development within the European ENSEMBLES project has been to explore performance-based weighting of regional climate models (RCMs). Until now, although no weighting has been applied in multi-RCM analyses, one could claim that an assumption of ‘equal weight’ was implicitly adopted.
JH Christensen +4 more
openaire +1 more source
Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Meteorologische Zeitschrift, 2008 Precipitation data from long-term high-resolution simulations with two regional climate models (CLM and REMO) are evaluated using a climatology based on observations for south-western Germany.
Hendrik Feldmann +6 more
doaj +1 more source
Use of the RegCM System over East Asia: Review and Perspectives
Engineering, 2017 The Abdus Salam International Center for Theoretical Physics (ICTP) RegCM system is one of the most commonly used regional climate models (RCMs) over the East Asia region.
Xuejie Gao, Filippo Giorgi
doaj +1 more source