Results 81 to 90 of about 17,691,603 (302)

The radiation budget in a regional climate model [PDF]

Climate Dynamics, 2010
The long- and short-wave components of the radiation budget are among the most important quantities in climate modelling. In this study, we evaluated the radiation budget at the earth’s surface and at the top of atmosphere over Europe as simulated by the regional climate model CLM.
Steffen Kothe, A. Dobler, A. Beck, B. Ahrens   +3 more
openaire   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

2019 San Diego Regional Climate Collaborative Annual Report [PDF]

, 2020
The San Diego Regional Climate Collaborative is a network for public agencies that serves the San Diego region to share expertise, leverage resources and advance comprehensive solutions to facilitate climate change planning.
San Diego Regional Climate Collaborative
core  

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source

Future changes in fog frequency from the UKCP09 ensemble of regional climate model projections [PDF]

, 2010
This report describes projections of the frequency of occurrence of fog derived from the UK Climate Projections 2009 (UKCP09) 11 member Regional Climate Model (RCM) simulations run at a 25 km resolution.
Murphy, James, Boorman, Penelope, Jenkins, Geoff   +2 more
core   +1 more source

A New Estimate of North American Mountain Snow Accumulation From Regional Climate Model Simulations

Geophysical Research Letters, 2018
Despite the importance of mountain snowpack to understanding the water and energy cycles in North America's montane regions, no reliable mountain snow climatology exists for the entire continent.
Melissa L. Wrzesien, Michael T. Durand, Tamlin M. Pavelsky, Sarah B. Kapnick, Yu Zhang, Junyi Guo, C. K. Shum   +6 more
doaj   +1 more source

Groundwater Rise Sustains the World's Largest Alpine Water System Under Global Warming

Advanced Science, EarlyView.
Shallow groundwater depth (SGWD) across the non‐permafrost plains of the Qinghai–Xizang Plateau decreased at averagely 0.02 m year−1, adding 31.44 Gt of freshwater storage from 2000 to 2020 and sustaining ∼53 500 km2 of alpine ecosystems. A vadose‐zone capacity of 426.6 Gt reveals these aquifers as promising reservoirs, highlighting groundwater's ...
Jianqing Du, Zhixiang Niu, Yanfen Wang, Shirui Zhou, Youqing Yang, Xiang Wei, Haishan Niu, Yitao Zhang, Anquan Xia, Yali Liu, Yanbin Hao, Kai Xue, Bingfang Wu, Xinquan Zhao, Tandong Yao, Yiyu Chen   +15 more
wiley   +1 more source

Runoff uncertainty associated with global climate model chosen in regional climate modeling [PDF]

Proceedings of the International Association of Hydrological Sciences
Uncertain climatic projections result in uncertain runoff predictions, which lead to unreliable water resources management and floods mitigation measures.
S. B. Ajjur, S. B. Ajjur, S. G. Al-Ghamdi, S. G. Al-Ghamdi, S. G. Al-Ghamdi   +4 more
doaj   +1 more source

Recapitulating In Vivo Pharmacokinetics and Size‐Dependent Nanomedicine Delivery in a Microfluidic Platform

Advanced Science, EarlyView.
A microfluidic tumor platform integrates pharmacokinetic flow control, vascular‐like barriers, and 3D tumor spheroids to emulate in vivo drug exposure. The system reproduces dynamic concentration–time profiles and enables size‐dependent nanoparticle transport and efficacy evaluation, providing a predictive framework for assessing nanomedicine ...
Su Jeong Kang, Moon Sup Yoon, Jae Min Lee, Min Jeong Jo, Chae Eun Jin, Dae Hwan Shin   +5 more
wiley   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source