Results 111 to 120 of about 35,822,390 (359)

Strategic-Based Regional Development: Towards a theory of everything for regional development?

open access: yesEuropean Journal of Spatial Development, 2022
This paper presents a potential ‘theory of everything’ for regional development processes which can be applied to development and cohesion policies. Denominated as strategic-based regional development, this more comprehensive regional development theoretical background embraces several established regional development paradigms, which include ...
openaire   +4 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Development Effectiveness Overview (DEO) 2020: Executive Summary

open access: yes, 2020
The Development Effectiveness Overview (DEO) is an annual report produced by the IDB Group to share the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Tech, Smart Cities, and Regional Development in Contemporary Russia

open access: yes, 2019
With chapters on FinTech, the cost of technological growth, and innovation risk management, Tech, Smart Cities and Regional Development in Contemporary Russia grapples with ideas about technology and the intertwined issues that Russia faces in the 21st ...
B. Sergi
semanticscholar   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Regional Public Goods in Official Development Assistance [PDF]

open access: yes, 2001
This paper seeks to review the demand, and the case, for regional public goods in the light of growing integration; to report on the response of certain international organizations and the system of official development assistance to perceived growth in ...
Inter-American Development Bank
core   +1 more source

Region, regionalization and local development

open access: yesTERRITORIAL IDENTITY AND DEVELOPMENT, 2017
This contribution aims to stimulate a critical reflection about local development, with particular attention to the role of regionalization practices in the construction of territorial identity processes. It is believed that the identification of specific areas is essential in public policies that aim to promote local specificities, especially in ...
openaire   +3 more sources

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