Results 141 to 150 of about 19,081,484 (363)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Regional development processes and policies [PDF]
, 1989 Technologic change, increased international economic competition, and associated reorganization of goods and service producing entities are resulting in a restructuring of economies in the developed world.
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Remote SensingAccurate in-season crop type mapping is critical for agricultural monitoring and yield assessment, yet most operational products remain proprietary, post-seasonal or insufficiently tested across contrasting seasons.
Sneha Sharma +4 more
doaj +1 more source
Regional Development and Regional Culture
Studies in Regional Science, 1992 Development of a region means an entity of both cultural and economic development, especially from the long term view point. But so called technical analysis for the regional development is usually confined to the economic phenomena.In this paper from the following proints of sense, I would like to consider the relation between regional development and
openaire +2 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Region, regionalization and local development
TERRITORIAL IDENTITY AND DEVELOPMENT, 2017 This contribution aims to stimulate a critical reflection about local development, with particular attention to the role of regionalization practices in the construction of territorial identity processes. It is believed that the identification of specific areas is essential in public policies that aim to promote local specificities, especially in ...
openaire +3 more sources
REGIONAL DEVELOPMENT AND SOCIO-ECONOMIC DIVERSITY IN ROMANIA [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2014 During the economic and political changes that took place in Europe and in Romania after 1989, it was imposed and also made important steps in the foundation of a new concept and a new regional development policy. Regional development policy in Romania
EMILIAN M. DOBRESCU +1 more
doaj