Results 41 to 50 of about 951,472 (288)

Urban Sprawl Characteristics and Typologies in Romania [PDF]

Human Geographies: Journal of Studies and Research in Human Geography, 2010
Urban sprawl limitation, moderate use of agricultural fields and ensuring the social mix are objectives of public policy of all European Community documents refering to urban and territorial planning, housing policies and territorial cohesion.
Bogdan Suditu, Anca Ginavar, Ana Muică, Crenguţa Iordăchescu, Amalia Vârdol, Bogdan Ghinea   +5 more
doaj  

Entrepreneurship and regional development [PDF]

, 2009
This chapter offers a review on modern entrepreneurship analysis, against the background of regional development. After a conceptual discussion on the importance and the measurement of entrepreneurship, the contribution discusses success factors and determinants of entrepreneurships.
Fischer, M.M., Nijkamp, P.
openaire   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

MAKING A LIVING ON CORAL ATOLL: CHANGING STRATEGIES AMONG MILLENNIALS ON BALOBALOANG ISLAND, SOUTH SULAWESI, INDONESIA

Journal of Asian Rural Studies, 2021
Beginning around 2014, some significant changes in the livelihoods among many younger men from the Island of Balobaloang, South Sulawesi, Indonesia, emerged.  This study describes and explains how it is that approximately 50 working-age adult men (out of
Gene Ammarell, Muslimin Muslimin, Sukur Oda, Ahmad Faisal R   +3 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Rural development and regional policy: Conceptual framework [PDF]

Facta Universitatis. Series: Architecture and Civil Engineering, 2010
The paper treats the potential of incorporation of the rural development into the planning framework of regulation of a more uniform regional development.
Vasilevska Ljiljana
doaj   +1 more source

Nexus of geoenvironment, resource management and regional sustainable development: Introduction [PDF]

, 2023
Jawad Abbas, Joanna Kurowska‐Pysz, Şerife Zihni Eyüpoğlu, Wei Liu   +3 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Landscape function analysis as a base of landscape visions

Acta Universitatis Sapientiae: Agriculture and Environment, 2015
An essential condition for the success of rural areas is the harmonious enforcement of ecologic, economic, and other educational, cultural, aesthetic goods/services of landscape, diversity of landscape functions.
Filepné Kovács Krisztina, Valánszki István, Sallay Ágnes, Jombach Sándor, Mikházi Zsuzsanna, Kollányi László   +5 more
doaj   +1 more source