Results 71 to 80 of about 915,789 (298)

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

REGIONAL DEVELOPMENT AND SOCIO-ECONOMIC DIVERSITY IN ROMANIA [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2014
During the economic and political changes that took place in Europe and in Romania after 1989, it was imposed and also made important steps in the foundation of a new concept and a new regional development policy. Regional development policy in Romania
EMILIAN M. DOBRESCU   +1 more
doaj  

Public Diplomacy Effort Across Facebook: A Comparative Analysis of the U.S. Consulate in Erbil and the Kurdistan Representation in Washington

open access: yesSAGE Open, 2018
Widespread communication tools such as Facebook and Twitter have become vital channels of public diplomacy. Today, policymakers must implement a successful Facebook diplomacy to enhance their nation’s branding, lobbying, and culture exchange and to ...
Ahmed Omar Bali   +2 more
doaj   +1 more source

Regional Development in Poland

open access: yesEUROPEAN RESEARCH STUDIES JOURNAL, 2023
PURPOSE: The multidimensionality of regional development allows its issues to be viewed from various perspectives. The article aims to quantify the research area named in the title and to classify the voivodeships in Poland; that is, to segment the studied regions into subsets where development similarity is preserved.
openaire   +2 more sources

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

open access: yesFEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson   +5 more
wiley   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

open access: yesFEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma   +10 more
wiley   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

open access: yesFEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui   +3 more
wiley   +1 more source

Viticulture – Challenge for Tourism Development (Znojmo Case Study Area)

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2014
The article, which deals with the issue whether the viticulture can be the challenge for tourism development, is based on research conducted in Znojmo case study area (the Czech Republic). It starts with general introduction of wine tourism concept based
Miroslav Foret   +2 more
doaj   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

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