Results 81 to 90 of about 921,239 (238)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

Disrupting comfort: From low-carbon to low-impact cities

open access: yesRaumforschung und Raumordnung
In this commentary, we argue for the low-impact city as an alternative to the dominant urban imaginary of the low-carbon city. We adopt an ecological economics lens to expose the limitations of the urban resource efficiency paradigm when tackling ...
Alejandro De Castro Mazarro   +2 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

Potential Economic Impact of Grapevine Phylloxera (Hemiptera: Phylloxeridae) on Western Australian Winegrapes

open access: yesAustralian Journal of Grape and Wine Research
Grapevine phylloxera Daktulosphaira vitifoliae Fitch (Hemiptera: Phylloxeridae) has been present in Australia for almost 150 years but has not spread to south-west Western Australia, in part due to the relative isolation of the region.
David C. Cook   +6 more
doaj   +1 more source

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee   +7 more
wiley   +1 more source

Mapping access to medical service provision at micro-scale: Dynamics in supply and demand in Germany

open access: yesRaumforschung und Raumordnung
This paper demonstrates an approach to the problem of micro-scale analysis of medical service provision in Germany. Research focuses include estimating population dynamics, mapping access to medical facilities and identifying spatial patterns in medical
Denis Reiter   +2 more
doaj   +1 more source

Regional Development in Romania

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Regional development policy is a policy of investment for economic development by supporting competitiveness, increasing the standards of living, improving the quality of life, creating new jobs. Regions and regional development policy occupies in recent
Remus Gherman   +3 more
doaj  

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

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