Results 81 to 90 of about 951,472 (288)

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez   +12 more
wiley   +1 more source

Amyotrophic Lateral Sclerosis Prevalence Projection in 2040: A Less Rare Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To project ALS prevalence across multiple countries through 2040, accounting for both population aging and increased survival. Methods Data from the Piemonte and Valle d'Aosta ALS register (PARALS) was used to estimate the trends in incidence and prevalence from 2005 to 2019. Survival trends over this period were also assessed.
Rosario Vasta   +18 more
wiley   +1 more source

Disrupting comfort: From low-carbon to low-impact cities

open access: yesRaumforschung und Raumordnung
In this commentary, we argue for the low-impact city as an alternative to the dominant urban imaginary of the low-carbon city. We adopt an ecological economics lens to expose the limitations of the urban resource efficiency paradigm when tackling ...
Alejandro De Castro Mazarro   +2 more
doaj   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu   +9 more
wiley   +1 more source

Potential Economic Impact of Grapevine Phylloxera (Hemiptera: Phylloxeridae) on Western Australian Winegrapes

open access: yesAustralian Journal of Grape and Wine Research
Grapevine phylloxera Daktulosphaira vitifoliae Fitch (Hemiptera: Phylloxeridae) has been present in Australia for almost 150 years but has not spread to south-west Western Australia, in part due to the relative isolation of the region.
David C. Cook   +6 more
doaj   +1 more source

Science and Technology Parks: Opening the Pandora's Box of Regional Development. [PDF]

open access: yesJ Knowl Econ, 2022
Gomes S   +3 more
europepmc   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen   +5 more
wiley   +1 more source

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