Results 41 to 50 of about 4,547,026 (311)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Space standard of formal employment in Paraná

open access: yesEconomia & Região, 2017
The paper analyzes the spatial profile of the location of formal employment in the Paraná State in Brazil, between 2002 and 2011. For the analysis we used the measures of location for analysis of economic sectors between the regions and among them was ...
Ariana Cericatto da Silva   +2 more
doaj   +1 more source

Regional economy management

open access: yesInternational journal of business, economics & management, 2022
This paper focused on the discussion to answer the problems of regional economic governance and how scientific evidence of the use of Technology can be a prospect and challenge in Indonesia's efforts to develop poor areas into prosperous areas. We study with a phenomenological approach that begins with in-depth data analysis techniques, thorough ...
Benny Rojeston Marnaek Nainggolan   +4 more
openaire   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

An Empirical Study on the Employment Monitoring and Early Warning Mechanism of Medical Graduates in Universities with Big Data and Complex Computing System

open access: yesDiscrete Dynamics in Nature and Society, 2021
Based on the management of big data, the analysis and forecast of the employment demand cycle business situation studied in this article is based on the employment cycle theory and a complete set of employment monitoring, employment evaluation ...
Haixia Wu, Sang-Bing Tsai
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Patentability of Patent Evergreening in the Pharmaceutical Sector: Novartis AG versus The Union of India

open access: yesAdliya
This paper discusses the inventions in the pharmaceutical sector containing the nature of 'evergreening' based on the Supreme Court of India's ruling in Novartis's versus the Union of India.
Tommy Hendrix, Angga Wijaya Holman
doaj   +1 more source

Digital-related economy sectors and regional economy disruption

open access: yesJurnal Ekonomi dan Bisnis, 2019
While the study of the regional economy and its factors has been well-researched, relatively less is known on the issues for the digital economy sectors affecting the regional economy.
Achmad Nurdany, Anggari Marya Kresnowati
doaj   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Energy Policy and Regional Inequalities in the Brazilian Economy [PDF]

open access: yes, 2010
The objective of this paper is to evaluate the long-run regional impacts of tariff policy of the Brazilian electric power sector. The structural reforms carried on this sector determined the emergence of two different spatial distribution trends of the ...
Haddad, Eduardo   +2 more
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