Results 171 to 180 of about 221,586 (310)

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

open access: yesAdvanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang   +11 more
wiley   +1 more source

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

open access: yesAdvanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin   +13 more
wiley   +1 more source

Regions and welfare expansion in the EU

open access: yes, 2011
Welfare states in the post II World War (WWII) period have often deployed a centralized mode of policy-making, which has tended to make equality and homogenization synonymous notions. According to this view, citizens’ social entitlements ought to be provided in a unitary --and generally centralized-- administration of public services.
openaire   +1 more source

Tendencies in the Romania's Regional Economic Development during the Period 1991-2004

open access: yes
The objective of this paper represents the analysis of the way the Romania's economic integration in the EU will influence the regional specialization and industrial activities localization within NUTS (the eight regions of Romania) during the period ...
Vlad, Liviu Bogdan   +2 more
core  

The Dynamics of Economic Policy and Regional Specialization: Evidence from China¡¯s High-tech Industry [PDF]

open access: yes
: This paper investigates the effects of economic policy on regional specialization of China¡¯s high-tech industries for the period 1996 to 2005. Results indicate that the average level of regional specialization increases over years.
Dan Zheng
core  

Evolution of the Healthcare System in Saudi Arabia Over the Last Century: A Historical and Policy Analysis. [PDF]

open access: yesJ Healthc Leadersh
Sheerah HA   +9 more
europepmc   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

open access: yesAdvanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi   +23 more
wiley   +1 more source

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