Results 21 to 30 of about 433,758 (312)

Regional governance and democracy [PDF]

open access: yes, 2018
The aim of this chapter is to explore the relationship between regional governance and democracy. Enhancing local democracy is often cited as one of the motivations behind regionalism, alongside efforts to boost economic development and transform public services.
openaire   +1 more source

Prevalence and associated risk factors for diabetic retinopathy at first ophthalmological contact

open access: yesAsian Journal of Medical Sciences, 2021
Background: Type 2 diabetes mellitus (DM) is now considered as a growing global public health concern due to cost associated with diabetic micro and macrovascular complications.
Bhavkaran Singh   +3 more
doaj   +1 more source

Regional Drought Resilience Plan for South West Queensland 2022-2030 [PDF]

open access: yes, 2023
he South West Queensland region is often referred to as the ‘Cornerstone’ of Queensland. The region’s area is 319,808km² – almost one fifth of the area of the state – and is home to 23,777 residents (ABS 2021).
Drysdale, A.   +9 more
core  

Polish Regional Elite Career Paths and the Impact of a Multilevel System

open access: yesPolitics in Central Europe, 2020
This paper aims to investigate the multilevel careers of members of Polish regional executives from the first direct election to regional parliaments in 1998 until the end of 2014.
Majchierkiewicz Tatiana
doaj   +1 more source

The entrepreneurial region? Evolving regional government roles in bioeconomy governance

open access: yesRegional Studies, Regional Science
The downscaling of environmental responsibilities poses new challenges for regional governments, necessitating an evolution in their roles to manage environmental policy alongside traditional local development duties. This paper draws on the concept of the entrepreneurial state and on the idea of the 'entrepreneurial region' to explore how local and ...
Diana Morales, Iryna Fil Kristensen
openaire   +2 more sources

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

The role of multi-stakeholders in the preservation of the Javanese language: Synergy between pawiyatan permadani, universities, and the regency government

open access: yesDiglosia
This study aims to (1) describe the multi-sector contribution to efforts to preserve the Javanese language in Wonosobo Regency, (2) identify inhibiting and supporting factors, and (3) describe strategies to increase the use of Javanese among the younger
Muhtar Sofwan Hidayat   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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